Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PemK-MazE
Location 474968..475512 Replicon chromosome
Accession NZ_FO082820
Organism Pseudorhizobium banfieldiae strain NT-26

Toxin (Protein)


Gene name mazF Uniprot ID L0NBE3
Locus tag NT26_RS02235 Protein ID WP_052637161.1
Coordinates 475189..475512 (+) Length 108 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID L0NAV6
Locus tag NT26_RS02230 Protein ID WP_052641742.1
Coordinates 474968..475192 (+) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NT26_RS02205 470206..471069 + 864 WP_052637157.1 S49 family peptidase -
NT26_RS02210 471091..471282 + 192 WP_052637158.1 hypothetical protein -
NT26_RS02215 471393..472328 + 936 WP_052641737.1 glycine--tRNA ligase subunit alpha -
NT26_RS02220 472400..472951 + 552 WP_052637159.1 LemA family protein -
NT26_RS02225 472964..474889 + 1926 WP_052637160.1 DUF2207 domain-containing protein -
NT26_RS02230 474968..475192 + 225 WP_052641742.1 antitoxin MazE family protein Antitoxin
NT26_RS02235 475189..475512 + 324 WP_052637161.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
NT26_RS02240 475669..477954 + 2286 WP_052637162.1 glycine--tRNA ligase subunit beta -
NT26_RS02245 478078..478521 - 444 WP_052637163.1 hypothetical protein -
NT26_RS02250 478610..479875 - 1266 WP_052637164.1 phosphoribosylamine--glycine ligase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(2-103)

Antitoxin

Antitoxin MazE-like

(6-68)


Sequences

Toxin        


Download         Length: 108 a.a.        Molecular weight: 11669.81 Da        Isoelectric Point: 10.8980

>T284885 WP_052637161.1 NZ_FO082820:475189-475512 [Pseudorhizobium banfieldiae]
MRRGDLVTIALPGDFSKPRPALIIQSDLFAETGTVTVLLVSATIVEAPLIRVTVHPSAANRLRKISQVMVDKAMSVKRDK
LGPTFGRLEDESMLAVNRSLAVFLNIL

Download         Length: 324 bp

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8143.30 Da        Isoelectric Point: 5.0488

>AT284885 WP_052641742.1 NZ_FO082820:474968-475192 [Pseudorhizobium banfieldiae]
MAIPVNKRVEKRREALRLAGLRPVQIWVPDTRQEGFVAECRRQASLVAAADAIDADLDAFLQAALGQLDRDGEA

Download         Length: 225 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB L0NBE3

Antitoxin

Source ID Structure
AlphaFold DB L0NAV6

References