284878

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) spoIISABC/SpoIISA-SpoIISB
Location 1345189..1346106 Replicon chromosome
Accession NZ_CP128551
Organism Bacillus velezensis strain SRCM123441

Toxin (Protein)


Gene name spoIISA Uniprot ID I2HQ15
Locus tag QTN52_RS06765 Protein ID WP_007407256.1
Coordinates 1345360..1346106 (-) Length 249 a.a.

Antitoxin (Protein)


Gene name spoIISB Uniprot ID I2HQ14
Locus tag QTN52_RS06760 Protein ID WP_003154807.1
Coordinates 1345189..1345359 (-) Length 57 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QTN52_RS06710 (1340396) 1340396..1340908 + 513 WP_017417605.1 sigma-70 family RNA polymerase sigma factor -
QTN52_RS06715 (1341021) 1341021..1341572 + 552 Protein_1262 terminase -
QTN52_RS06720 (1341683) 1341683..1342045 + 363 WP_014721043.1 hypothetical protein -
QTN52_RS06725 (1342058) 1342058..1342429 + 372 WP_017417608.1 XkdW family protein -
QTN52_RS06730 (1342434) 1342434..1342631 + 198 WP_007610833.1 XkdX family protein -
QTN52_RS06735 (1342688) 1342688..1343449 + 762 WP_017417609.1 hypothetical protein -
QTN52_RS06740 (1343500) 1343500..1343763 + 264 WP_003154815.1 hemolysin XhlA family protein -
QTN52_RS06745 (1343777) 1343777..1344040 + 264 WP_003154813.1 phage holin -
QTN52_RS06750 (1344054) 1344054..1344932 + 879 WP_007407257.1 N-acetylmuramoyl-L-alanine amidase -
QTN52_RS06755 (1344967) 1344967..1345092 - 126 WP_003154809.1 hypothetical protein -
QTN52_RS06760 (1345189) 1345189..1345359 - 171 WP_003154807.1 type II toxin-antitoxin system SpoIISB family antitoxin Antitoxin
QTN52_RS06765 (1345360) 1345360..1346106 - 747 WP_007407256.1 type II toxin-antitoxin system SpoIISA family toxin Toxin
QTN52_RS06770 (1346210) 1346210..1347208 - 999 WP_017417610.1 inorganic phosphate transporter -
QTN52_RS06775 (1347221) 1347221..1347838 - 618 WP_003154804.1 DUF47 domain-containing protein -
QTN52_RS06780 (1348125) 1348125..1349441 - 1317 WP_134986489.1 amino acid permease -
QTN52_RS06785 (1349763) 1349763..1350713 + 951 WP_007610844.1 ring-cleaving dioxygenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SpoIISA, type II toxin-antitoxin system

(3-239)

Antitoxin

Antitoxin SpoIISB

(1-56)


Sequences

Toxin        


Download         Length: 249 a.a.        Molecular weight: 29077.57 Da        Isoelectric Point: 4.7755

>T284878 WP_007407256.1 NZ_CP128551:c1346106-1345360 [Bacillus velezensis]
MLLFFQIMVWTMAAALILYVYASWRYEAKVKEKMFAIRKTWYLLFVLGSMVYWTYDPESLFAAWRQYLIVAVCFALIDAF
IFLSAYIKKLAGNELETDTREILEENNEMLHSYLEKLKTYQYLLKNEPIHVYYGSTEAYAEGISRLLAAYAEKMNVTASL
CDYSAQSDKDRLTEHMPDAADVQSRLNRKDVYYDQKGRLVLIPFTVQNRHYVIKLTSENLLTEFDYLLFTSLTSIYDLML
PIEEEGDG

Download         Length: 747 bp

Antitoxin


Download         Length: 57 a.a.        Molecular weight: 6676.74 Da        Isoelectric Point: 10.9273

>AT284878 WP_003154807.1 NZ_CP128551:c1345359-1345189 [Bacillus velezensis]
MEQAFQNGQPEQRAKPFKMFKKRSMTSIASYQVSPHTARIFKENERLIDKYKQKKA

Download         Length: 171 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB I2HQ15

Antitoxin

Source ID Structure
AlphaFold DB I2HQ14

References