Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 4814746..4815262 Replicon chromosome
Accession NZ_CP128549
Organism Pseudomonas monteilii strain NMI985_06

Toxin (Protein)


Gene name relE Uniprot ID A0A3G2HKE7
Locus tag LU680_RS22765 Protein ID WP_016712032.1
Coordinates 4814746..4815033 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A446A2J5
Locus tag LU680_RS22770 Protein ID WP_028700126.1
Coordinates 4815023..4815262 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LU680_RS22750 (LU680_22750) 4809785..4812664 + 2880 WP_016712029.1 ribonucleoside-diphosphate reductase subunit alpha -
LU680_RS22755 (LU680_22755) 4812804..4812935 + 132 WP_016712030.1 hypothetical protein -
LU680_RS22760 (LU680_22760) 4813382..4814632 + 1251 WP_016712031.1 ribonucleotide-diphosphate reductase subunit beta -
LU680_RS22765 (LU680_22765) 4814746..4815033 - 288 WP_016712032.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LU680_RS22770 (LU680_22770) 4815023..4815262 - 240 WP_028700126.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
LU680_RS22775 (LU680_22775) 4815863..4817101 + 1239 WP_016712034.1 OprD family porin -
LU680_RS22780 (LU680_22780) 4817265..4818071 + 807 WP_016712035.1 NAD(P)-dependent oxidoreductase -
LU680_RS22785 (LU680_22785) 4818098..4818979 + 882 WP_016712036.1 SMP-30/gluconolactonase/LRE family protein -
LU680_RS22790 (LU680_22790) 4819045..4820016 + 972 WP_063977227.1 TRAP transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(9-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-79)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11233.07 Da        Isoelectric Point: 9.9006

>T284868 WP_016712032.1 NZ_CP128549:c4815033-4814746 [Pseudomonas monteilii]
MTYSLDFDCRALKEWKKLGDTVREQFKKKLAEVLLNPRVEANRLHSLPDCYKIKLRSSGYRLVYQVIGQEIVVFVVAVDR
RERDQAYKKAAERLE

Download         Length: 288 bp

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9111.46 Da        Isoelectric Point: 4.6310

>AT284868 WP_028700126.1 NZ_CP128549:c4815262-4815023 [Pseudomonas monteilii]
MASINIRVDDDLKARAYKELERLGVTPSELMRQALQYVAERGKLPFRPVLMTEEDEDLIATVQERLASPQRVRVQLDDL

Download         Length: 240 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2HKE7

Antitoxin

Source ID Structure
AlphaFold DB A0A446A2J5

References