Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 4862844..4863430 Replicon chromosome
Accession NZ_CP128548
Organism Pseudomonas kurunegalensis strain NMI3456_12

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag LU664_RS23115 Protein ID WP_082426425.1
Coordinates 4863137..4863430 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID A0A923H277
Locus tag LU664_RS23110 Protein ID WP_060499950.1
Coordinates 4862844..4863140 (-) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LU664_RS23090 (LU664_023090) 4859812..4860753 - 942 WP_164525071.1 FecR domain-containing protein -
LU664_RS23095 (LU664_023095) 4860753..4861265 - 513 WP_164525274.1 sigma-70 family RNA polymerase sigma factor -
LU664_RS23100 (LU664_023100) 4861555..4862202 + 648 WP_060499948.1 hypothetical protein -
LU664_RS23105 (LU664_023105) 4862354..4862842 + 489 WP_164525072.1 GNAT family N-acetyltransferase -
LU664_RS23110 (LU664_023110) 4862844..4863140 - 297 WP_060499950.1 putative addiction module antidote protein Antitoxin
LU664_RS23115 (LU664_023115) 4863137..4863430 - 294 WP_082426425.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LU664_RS23120 (LU664_023120) 4863652..4864539 + 888 WP_164525073.1 bestrophin family ion channel -
LU664_RS23125 (LU664_023125) 4864536..4865303 - 768 WP_060499952.1 phosphonate ABC transporter, permease protein PhnE -
LU664_RS23130 (LU664_023130) 4865300..4866127 - 828 WP_060499953.1 ABC transporter permease subunit -
LU664_RS23135 (LU664_023135) 4866121..4866930 - 810 WP_164525074.1 ATP-binding cassette domain-containing protein -
LU664_RS23140 (LU664_023140) 4866927..4867781 - 855 WP_164525075.1 putative selenate ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(4-95)

Antitoxin

Uncharacterized protein HI1420

(4-93)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10847.80 Da        Isoelectric Point: 10.5184

>T284866 WP_082426425.1 NZ_CP128548:c4863430-4863137 [Pseudomonas kurunegalensis]
MYLVEQTESFAVWLSSLRDLKAKLAIGRRLERVAIGNLGDFKWLGGGLGELRIDVGAGYRVYFTQKGHRLVLLLVGGDKS
TQVADILKSRKLLKEMI

Download         Length: 294 bp

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 10587.22 Da        Isoelectric Point: 6.2205

>AT284866 WP_060499950.1 NZ_CP128548:c4863140-4862844 [Pseudomonas kurunegalensis]
MSEKLIPFDMAALLSSDEAISEYLSQVLSDGDTEEIIRALGHIARARGMTHIATESGLGRESLYKALSPGAKPRFDTVLK
VIRALGVDLLVQPHAVAR

Download         Length: 297 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References