Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/RHH(antitoxin)
Location 3473687..3474240 Replicon chromosome
Accession NZ_CP128548
Organism Pseudomonas kurunegalensis strain NMI3456_12

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag LU664_RS16320 Protein ID WP_164524678.1
Coordinates 3473687..3473980 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LU664_RS16325 Protein ID WP_096862010.1
Coordinates 3473968..3474240 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LU664_RS16280 (LU664_016280) 3468691..3468945 + 255 WP_164524675.1 hypothetical protein -
LU664_RS16285 (LU664_016285) 3468942..3469508 + 567 WP_060497295.1 hypothetical protein -
LU664_RS16290 (LU664_016290) 3469552..3469875 + 324 WP_060497296.1 helix-turn-helix transcriptional regulator -
LU664_RS16295 (LU664_016295) 3469931..3470257 + 327 WP_060497297.1 hypothetical protein -
LU664_RS16300 (LU664_016300) 3470320..3470496 + 177 WP_164524676.1 hypothetical protein -
LU664_RS16305 (LU664_016305) 3470516..3470920 + 405 WP_232905530.1 hypothetical protein -
LU664_RS16310 (LU664_016310) 3470806..3471969 + 1164 Protein_3189 tyrosine-type recombinase/integrase -
LU664_RS16315 (LU664_016315) 3472284..3473693 + 1410 WP_164524677.1 site-specific integrase -
LU664_RS16320 (LU664_016320) 3473687..3473980 - 294 WP_164524678.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LU664_RS16325 (LU664_016325) 3473968..3474240 - 273 WP_096862010.1 CopG family ribbon-helix-helix protein Antitoxin
LU664_RS16330 (LU664_016330) 3474675..3476402 - 1728 WP_217989239.1 GTPase domain-containing protein -
LU664_RS16335 (LU664_016335) 3476389..3478125 - 1737 WP_164524681.1 hypothetical protein -
LU664_RS16340 (LU664_016340) 3478126..3478731 - 606 WP_164524682.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island aph(3'')-Ib / aph(6)-Id / blaVIM-2 / sul1 / tet(G) / floR / aac(6')-IIa / cmlA1 - 3466665..3547220 80555


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-95)

Antitoxin

Ribbon-helix-helix protein, CopG

(3-40)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11183.67 Da        Isoelectric Point: 5.9081

>T284863 WP_164524678.1 NZ_CP128548:c3473980-3473687 [Pseudomonas kurunegalensis]
VPRLIVTEGAAKGLERCRRFLSDKDPQVARRAAQVIERQFARLEESPEVGRPFPDLPELRELIIEFGDSGYVALYRYERA
DDTAYVLAFRHQKEAGY

Download         Length: 294 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10494.66 Da        Isoelectric Point: 6.7193

>AT284863 WP_096862010.1 NZ_CP128548:c3474240-3473968 [Pseudomonas kurunegalensis]
MATSIKIDDKLKGRIQQLASQRQRSSHWIMREAITQYVEREEARESFKQEALASWAAYQETGRHLTSQETRTWLGSWGTD
TEAELPKCHD

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References