Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 4675331..4675847 Replicon chromosome
Accession NZ_CP128546
Organism Pseudomonas monteilii strain NMI8712_11

Toxin (Protein)


Gene name relE Uniprot ID A0A3G2HKE7
Locus tag LU654_RS21880 Protein ID WP_016712032.1
Coordinates 4675331..4675618 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A446A2J5
Locus tag LU654_RS21885 Protein ID WP_028700126.1
Coordinates 4675608..4675847 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LU654_RS21865 (LU654_021865) 4670370..4673249 + 2880 WP_016712029.1 ribonucleoside-diphosphate reductase subunit alpha -
LU654_RS21870 (LU654_021870) 4673389..4673520 + 132 WP_016712030.1 hypothetical protein -
LU654_RS21875 (LU654_021875) 4673967..4675217 + 1251 WP_016712031.1 ribonucleotide-diphosphate reductase subunit beta -
LU654_RS21880 (LU654_021880) 4675331..4675618 - 288 WP_016712032.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LU654_RS21885 (LU654_021885) 4675608..4675847 - 240 WP_028700126.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
LU654_RS21890 (LU654_021890) 4676448..4677686 + 1239 WP_016712034.1 OprD family porin -
LU654_RS21895 (LU654_021895) 4677850..4678656 + 807 WP_016712035.1 NAD(P)-dependent oxidoreductase -
LU654_RS21900 (LU654_021900) 4678683..4679564 + 882 WP_016712036.1 SMP-30/gluconolactonase/LRE family protein -
LU654_RS21905 (LU654_021905) 4679630..4680601 + 972 WP_063977227.1 TRAP transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(9-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-79)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11233.07 Da        Isoelectric Point: 9.9006

>T284857 WP_016712032.1 NZ_CP128546:c4675618-4675331 [Pseudomonas monteilii]
MTYSLDFDCRALKEWKKLGDTVREQFKKKLAEVLLNPRVEANRLHSLPDCYKIKLRSSGYRLVYQVIGQEIVVFVVAVDR
RERDQAYKKAAERLE

Download         Length: 288 bp

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9111.46 Da        Isoelectric Point: 4.6310

>AT284857 WP_028700126.1 NZ_CP128546:c4675847-4675608 [Pseudomonas monteilii]
MASINIRVDDDLKARAYKELERLGVTPSELMRQALQYVAERGKLPFRPVLMTEEDEDLIATVQERLASPQRVRVQLDDL

Download         Length: 240 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2HKE7

Antitoxin

Source ID Structure
AlphaFold DB A0A446A2J5

References