Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 4700184..4700700 Replicon chromosome
Accession NZ_CP128545
Organism Pseudomonas monteilii strain NMI6266_12

Toxin (Protein)


Gene name relE Uniprot ID A0A3G2HKE7
Locus tag LU662_RS22420 Protein ID WP_016712032.1
Coordinates 4700184..4700471 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A446A2J5
Locus tag LU662_RS22425 Protein ID WP_028700126.1
Coordinates 4700461..4700700 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LU662_RS22405 (LU662_022405) 4695223..4698102 + 2880 WP_016712029.1 ribonucleoside-diphosphate reductase subunit alpha -
LU662_RS22410 (LU662_022410) 4698242..4698373 + 132 WP_016712030.1 hypothetical protein -
LU662_RS22415 (LU662_022415) 4698820..4700070 + 1251 WP_016712031.1 ribonucleotide-diphosphate reductase subunit beta -
LU662_RS22420 (LU662_022420) 4700184..4700471 - 288 WP_016712032.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LU662_RS22425 (LU662_022425) 4700461..4700700 - 240 WP_028700126.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
LU662_RS22430 (LU662_022430) 4701301..4702539 + 1239 WP_016712034.1 OprD family porin -
LU662_RS22435 (LU662_022435) 4702703..4703509 + 807 WP_016712035.1 NAD(P)-dependent oxidoreductase -
LU662_RS22440 (LU662_022440) 4703536..4704417 + 882 WP_016712036.1 SMP-30/gluconolactonase/LRE family protein -
LU662_RS22445 (LU662_022445) 4704483..4705454 + 972 WP_063977227.1 TRAP transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(9-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-79)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11233.07 Da        Isoelectric Point: 9.9006

>T284855 WP_016712032.1 NZ_CP128545:c4700471-4700184 [Pseudomonas monteilii]
MTYSLDFDCRALKEWKKLGDTVREQFKKKLAEVLLNPRVEANRLHSLPDCYKIKLRSSGYRLVYQVIGQEIVVFVVAVDR
RERDQAYKKAAERLE

Download         Length: 288 bp

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9111.46 Da        Isoelectric Point: 4.6310

>AT284855 WP_028700126.1 NZ_CP128545:c4700700-4700461 [Pseudomonas monteilii]
MASINIRVDDDLKARAYKELERLGVTPSELMRQALQYVAERGKLPFRPVLMTEEDEDLIATVQERLASPQRVRVQLDDL

Download         Length: 240 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2HKE7

Antitoxin

Source ID Structure
AlphaFold DB A0A446A2J5

References