Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 3240875..3241412 Replicon chromosome
Accession NZ_CP128544
Organism Pseudomonas mosselii strain NMI4849_14

Toxin (Protein)


Gene name relE Uniprot ID A0A2T1A3Q3
Locus tag LU678_RS15595 Protein ID WP_017518825.1
Coordinates 3240875..3241156 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A2T1A3N8
Locus tag LU678_RS15600 Protein ID WP_017518824.1
Coordinates 3241143..3241412 (-) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LU678_RS15575 (LU678_015575) 3236344..3236469 + 126 WP_269807185.1 hypothetical protein -
LU678_RS15580 (LU678_015580) 3236466..3239432 - 2967 WP_143498254.1 Tn3-like element TnAs1 family transposase -
LU678_RS15585 (LU678_015585) 3239436..3239996 - 561 WP_010921730.1 recombinase family protein -
LU678_RS15590 (LU678_015590) 3240173..3240748 - 576 WP_001173919.1 recombinase family protein -
LU678_RS15595 (LU678_015595) 3240875..3241156 - 282 WP_017518825.1 type II toxin-antitoxin system YafQ family toxin Toxin
LU678_RS15600 (LU678_015600) 3241143..3241412 - 270 WP_017518824.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
LU678_RS15605 (LU678_015605) 3241656..3242645 - 990 WP_003132006.1 DUF3330 domain-containing protein -
LU678_RS15610 (LU678_015610) 3242642..3242878 - 237 WP_003132004.1 broad-spectrum mercury transporter MerE -
LU678_RS15615 (LU678_015615) 3242875..3243240 - 366 WP_000995360.1 mercury resistance co-regulator MerD -
LU678_RS15620 (LU678_015620) 3243258..3244943 - 1686 WP_003158917.1 mercury(II) reductase -
LU678_RS15625 (LU678_015625) 3245015..3245290 - 276 WP_003131987.1 mercury resistance system periplasmic binding protein MerP -
LU678_RS15630 (LU678_015630) 3245303..3245653 - 351 WP_003131974.1 mercuric ion transporter MerT -
LU678_RS15635 (LU678_015635) 3245725..3246159 + 435 WP_003131969.1 mercury resistance transcriptional regulator MerR -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-92)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(8-82)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10707.15 Da        Isoelectric Point: 8.9188

>T284852 WP_017518825.1 NZ_CP128544:c3241156-3240875 [Pseudomonas mosselii]
MRTIDRSSAFKRDYKREAKGQHRATLDDALKPVLVALATDQPLDARYRDHDLSGDWAGYRECHIKPDLLLIYRKSDPDIL
RLARLGSHSELFG

Download         Length: 282 bp

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9719.10 Da        Isoelectric Point: 5.6976

>AT284852 WP_017518824.1 NZ_CP128544:c3241412-3241143 [Pseudomonas mosselii]
MSTTADTYVRARIDTNTKERAASALEAMGLSISDAIRLLMLRIADEHRLPFDVKVPNATTKKAIAELEAGKGKKFTSVDD
LMADLHADD

Download         Length: 270 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2T1A3Q3

Antitoxin

Source ID Structure
AlphaFold DB A0A2T1A3N8

References