Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 5285533..5286173 Replicon chromosome
Accession NZ_CP128543
Organism Pseudomonas soli strain NMI4264_15

Toxin (Protein)


Gene name vapC Uniprot ID A0A1H9S264
Locus tag LU688_RS24405 Protein ID WP_028691288.1
Coordinates 5285763..5286173 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag LU688_RS24400 Protein ID WP_094012238.1
Coordinates 5285533..5285763 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LU688_RS24380 (LU688_24380) 5280990..5282315 - 1326 WP_038706878.1 precorrin-3B synthase -
LU688_RS24385 (LU688_24385) 5282427..5283638 + 1212 WP_160290830.1 precorrin-6y C5,15-methyltransferase (decarboxylating) subunit CbiE -
LU688_RS24390 (LU688_24390) 5283631..5284725 + 1095 WP_094012239.1 cobalt-precorrin-5B (C(1))-methyltransferase -
LU688_RS24395 (LU688_24395) 5284722..5285450 + 729 WP_160290816.1 cobalt-precorrin-6A reductase -
LU688_RS24400 (LU688_24400) 5285533..5285763 + 231 WP_094012238.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
LU688_RS24405 (LU688_24405) 5285763..5286173 + 411 WP_028691288.1 tRNA(fMet)-specific endonuclease VapC Toxin
LU688_RS24410 (LU688_24410) 5286246..5286683 + 438 WP_088852331.1 NfeD family protein -
LU688_RS24415 (LU688_24415) 5286710..5287564 + 855 WP_023631114.1 SPFH domain-containing protein -
LU688_RS24420 (LU688_24420) 5287676..5288065 + 390 WP_094012237.1 DUF2946 domain-containing protein -
LU688_RS24425 (LU688_24425) 5288113..5288598 + 486 WP_023631116.1 copper chaperone PCu(A)C -
LU688_RS24430 (LU688_24430) 5288619..5289044 + 426 WP_023631117.1 DUF2946 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-124)

Antitoxin

SpoVT-AbrB domain

(7-53)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15234.59 Da        Isoelectric Point: 9.5447

>T284849 WP_028691288.1 NZ_CP128543:5285763-5286173 [Pseudomonas soli]
MLRYMLDTNICIFTIKNKPQVVREAFNRHHGQLAISTVTLMELIYGAEKSAAPERNLAIVEGFAARLDVLDYDIQGAAHT
AQLRAELAKAGTPIGPYDRMIAGHARARGLTLVTNNLREFQRVPGLRVEDWVTHPR

Download         Length: 411 bp

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8445.33 Da        Isoelectric Point: 4.2683

>AT284849 WP_094012238.1 NZ_CP128543:5285533-5285763 [Pseudomonas soli]
MEQGAVFKSNRSQAIRMPKALALPDDVTRVDIVAVGRSRIISPAGESWDSWFEGDDVSSDFMASREQPADQEREGF

Download         Length: 231 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1H9S264

Antitoxin

Source ID Structure

References