Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 5063069..5063588 Replicon chromosome
Accession NZ_CP128543
Organism Pseudomonas soli strain NMI4264_15

Toxin (Protein)


Gene name relE Uniprot ID A0A1H9NMR5
Locus tag LU688_RS23330 Protein ID WP_023629498.1
Coordinates 5063298..5063588 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A2L0LWH9
Locus tag LU688_RS23325 Protein ID WP_023629499.1
Coordinates 5063069..5063308 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LU688_RS23310 (LU688_23310) 5058366..5058884 - 519 WP_023632629.1 histidine phosphatase family protein -
LU688_RS23315 (LU688_23315) 5058949..5061252 - 2304 WP_160290921.1 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase -
LU688_RS23320 (LU688_23320) 5061490..5062977 + 1488 WP_160290920.1 methylenetetrahydrofolate reductase C-terminal domain-containing protein -
LU688_RS23325 (LU688_23325) 5063069..5063308 + 240 WP_023629499.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
LU688_RS23330 (LU688_23330) 5063298..5063588 + 291 WP_023629498.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LU688_RS23335 (LU688_23335) 5063824..5064105 + 282 WP_023629497.1 Phd-YefM -
LU688_RS23340 (LU688_23340) 5064132..5064284 - 153 WP_158659585.1 hypothetical protein -
LU688_RS23345 (LU688_23345) 5064339..5065547 - 1209 WP_201754976.1 PAS domain-containing sensor histidine kinase -
LU688_RS23350 (LU688_23350) 5065540..5066352 - 813 WP_160290919.1 alpha/beta hydrolase -
LU688_RS23355 (LU688_23355) 5066817..5067596 + 780 WP_160290918.1 MarR family transcriptional regulator -
LU688_RS23360 (LU688_23360) 5067597..5068298 + 702 WP_094011755.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-69)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11378.22 Da        Isoelectric Point: 10.2588

>T284848 WP_023629498.1 NZ_CP128543:5063298-5063588 [Pseudomonas soli]
MTYNLDFDARALKEWQKLGDTIRQQLKKKLATVLLNPRVEANRLHGFPDCYKIKLRSSGYRLVYQVIDHQIVVFVVAVDK
RERDQVYRKAAERLTE

Download         Length: 291 bp

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9050.45 Da        Isoelectric Point: 4.8146

>AT284848 WP_023629499.1 NZ_CP128543:5063069-5063308 [Pseudomonas soli]
MASINVRIDDDLKVRAYRELEKLGVTPSELMRQALQYVAERGQLPFKPVLLTEEDEALLATVRERLASPQRVRVTLDDL

Download         Length: 240 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1H9NMR5

Antitoxin

Source ID Structure
AlphaFold DB A0A2L0LWH9

References