Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | pmenTA/darT(toxin) |
Location | 326485..328214 | Replicon | chromosome |
Accession | NZ_CP128543 | ||
Organism | Pseudomonas soli strain NMI4264_15 |
Toxin (Protein)
Gene name | pmenT | Uniprot ID | - |
Locus tag | LU688_RS01390 | Protein ID | WP_094011570.1 |
Coordinates | 326485..327126 (+) | Length | 214 a.a. |
Antitoxin (Protein)
Gene name | pmenA | Uniprot ID | - |
Locus tag | LU688_RS01395 | Protein ID | WP_094011569.1 |
Coordinates | 327126..328214 (+) | Length | 363 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
LU688_RS01370 (LU688_01370) | 322573..323088 | + | 516 | WP_038707192.1 | dihydrofolate reductase | - |
LU688_RS01375 (LU688_01375) | 323122..324513 | - | 1392 | WP_038707193.1 | L-cystine transporter | - |
LU688_RS01380 (LU688_01380) | 324758..325816 | + | 1059 | WP_023629699.1 | phosphorylcholine phosphatase | - |
LU688_RS01385 (LU688_01385) | 325907..326488 | + | 582 | WP_110605155.1 | DarT ssDNA thymidine ADP-ribosyltransferase family protein | - |
LU688_RS01390 (LU688_01390) | 326485..327126 | + | 642 | WP_094011570.1 | DUF4433 domain-containing protein | Toxin |
LU688_RS01395 (LU688_01395) | 327126..328214 | + | 1089 | WP_094011569.1 | macro domain-containing protein | Antitoxin |
LU688_RS01400 (LU688_01400) | 328278..330119 | - | 1842 | WP_094011568.1 | dihydroxy-acid dehydratase | - |
LU688_RS01405 (LU688_01405) | 330581..332257 | + | 1677 | WP_094011567.1 | DUF4153 domain-containing protein | - |
LU688_RS01410 (LU688_01410) | 332313..332714 | - | 402 | WP_023629701.1 | lysozyme inhibitor LprI family protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 214 a.a. Molecular weight: 24545.03 Da Isoelectric Point: 8.8650
>T284846 WP_094011570.1 NZ_CP128543:326485-327126 [Pseudomonas soli]
MTYTRLNPSKALIWRIVHRDNLPWLLDNGLCAVSRGNLSSGYVGIGNPDLISKRSRRAVPIDPGGTLADYVPFYFTPFSV
MMKNIHSGRGVQQRRNEEIVILVSSLYHVRSLGLPFVFTDAHAYPDWAGYYSDLEHLDKIDWQILQSRDFKRDPDDPRKM
ERYQAEALIHGHVPVAGLLGIVCYNEALQRRVDQEVRQRQLDLPVHARPGWYF
MTYTRLNPSKALIWRIVHRDNLPWLLDNGLCAVSRGNLSSGYVGIGNPDLISKRSRRAVPIDPGGTLADYVPFYFTPFSV
MMKNIHSGRGVQQRRNEEIVILVSSLYHVRSLGLPFVFTDAHAYPDWAGYYSDLEHLDKIDWQILQSRDFKRDPDDPRKM
ERYQAEALIHGHVPVAGLLGIVCYNEALQRRVDQEVRQRQLDLPVHARPGWYF
Download Length: 642 bp
Antitoxin
Download Length: 363 a.a. Molecular weight: 40527.43 Da Isoelectric Point: 6.1116
>AT284846 WP_094011569.1 NZ_CP128543:327126-328214 [Pseudomonas soli]
MIRFTQGNLLEAKAEALVNTVNTVGVMGKGIALMFKERFVENYRLYAAACKADEVVTGKMFITEVRELDGPRWVVNFPTK
RHWRSPSQLAWITDGLYDLRRFILANAVSSIAIPPLGAGNGGLPWAAVREQIEVVLGDLDTDVLVFEPTSKYQNVSKRTG
VEKLTPARALIAELVRRYWVLGMECSLLEIQKLAWFLERSIERFTPDDNPLNLQFSAHKYGPYTNRLEHLLNNLDGSYLH
CDKRIGDAGPLDVIWFDEGRKAFVDTYLHSEAKAYLPALEFTAELIDGFESPFGMELLATVDWLLHRDGVAPTVDAIRDG
LKNWSGGKEAATRKSALFDDDSLSVALKKLSAFHVQSASPVH
MIRFTQGNLLEAKAEALVNTVNTVGVMGKGIALMFKERFVENYRLYAAACKADEVVTGKMFITEVRELDGPRWVVNFPTK
RHWRSPSQLAWITDGLYDLRRFILANAVSSIAIPPLGAGNGGLPWAAVREQIEVVLGDLDTDVLVFEPTSKYQNVSKRTG
VEKLTPARALIAELVRRYWVLGMECSLLEIQKLAWFLERSIERFTPDDNPLNLQFSAHKYGPYTNRLEHLLNNLDGSYLH
CDKRIGDAGPLDVIWFDEGRKAFVDTYLHSEAKAYLPALEFTAELIDGFESPFGMELLATVDWLLHRDGVAPTVDAIRDG
LKNWSGGKEAATRKSALFDDDSLSVALKKLSAFHVQSASPVH
Download Length: 1089 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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