Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 3745726..3746609 Replicon chromosome
Accession NZ_CP128542
Organism Pseudomonas asiatica strain NMI3658_15

Toxin (Protein)


Gene name - Uniprot ID A0A0C1HTG7
Locus tag LU687_RS17780 Protein ID WP_015270851.1
Coordinates 3745726..3746163 (-) Length 146 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID F8G488
Locus tag LU687_RS17785 Protein ID WP_013973163.1
Coordinates 3746160..3746609 (-) Length 150 a.a.

Genomic Context

LU687_RS17760LU687_RS17770LU687_RS17775LU687_RS17795LU687_RS17800LU687_RS17805LU687_RS17765LU687_RS17780LU687_RS17785LU687_RS17790LU687_RS17810
Location: 3740954..3742018 (1065 bp)
Type: Others
Protein ID: WP_015270847.1
Location: 3743466..3744392 (927 bp)
Type: Others
Protein ID: WP_015270849.1
Location: 3744564..3745718 (1155 bp)
Type: Others
Protein ID: WP_015270850.1
Location: 3747466..3748389 (924 bp)
Type: Others
Protein ID: WP_015270853.1
Location: 3748437..3749267 (831 bp)
Type: Others
Protein ID: WP_015270854.1
Location: 3749318..3749902 (585 bp)
Type: Others
Protein ID: WP_015270855.1
Location: 3742096..3743325 (1230 bp)
Type: Others
Protein ID: WP_015270848.1
Location: 3745726..3746163 (438 bp)
Type: Toxin
Protein ID: WP_015270851.1
Location: 3746160..3746609 (450 bp)
Type: Antitoxin
Protein ID: WP_013973163.1
Location: 3746708..3747361 (654 bp)
Type: Others
Protein ID: WP_015270852.1
Location: 3750042..3751241 (1200 bp)
Type: Others
Protein ID: WP_043935712.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
LU687_RS17760 (LU687_017760)3740954..3742018+1065WP_015270847.1TerC family protein-
LU687_RS17765 (LU687_017765)3742096..3743325-1230WP_015270848.1acyl-CoA dehydrogenase-
LU687_RS17770 (LU687_017770)3743466..3744392+927WP_015270849.1LysR family transcriptional regulator-
LU687_RS17775 (LU687_017775)3744564..3745718+1155WP_015270850.1aminotransferase class V-fold PLP-dependent enzyme-
LU687_RS17780 (LU687_017780)3745726..3746163-438WP_015270851.1RES family NAD+ phosphorylaseToxin
LU687_RS17785 (LU687_017785)3746160..3746609-450WP_013973163.1DUF2384 domain-containing proteinAntitoxin
LU687_RS17790 (LU687_017790)3746708..3747361-654WP_015270852.1oxygen-insensitive NAD(P)H-dependent nitroreductase NfsB-
LU687_RS17795 (LU687_017795)3747466..3748389+924WP_015270853.1LysR family transcriptional regulator-
LU687_RS17800 (LU687_017800)3748437..3749267+831WP_015270854.1AraC family transcriptional regulator-
LU687_RS17805 (LU687_017805)3749318..3749902+585WP_015270855.1LysE family translocator-
LU687_RS17810 (LU687_017810)3750042..3751241-1200WP_043935712.1sugar transporter-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(3-137)

Antitoxin

Antitoxin Xre-like, helix-turn-helix domain

(33-91)


Sequences

Toxin        


Download         Length: 146 a.a.        Molecular weight: 15969.19 Da        Isoelectric Point: 5.1199

>T284844 WP_015270851.1 NZ_CP128542:c3746163-3745726 [Pseudomonas asiatica]
VILWRISAYADLSGTGGLRVSGRWHQAGRPVVYAATSPAGAMLEVLVHLEIDPEDFPTTMRLLRIELPDTVSQAQLPALQ
PGWSSQTELTRGLGNRFLDECSALLLPVPSAIMPSTTNYLFNPRHPQANSARLEVEDFTPDSRLF

Download         Length: 438 bp

Antitoxin


Download         Length: 150 a.a.        Molecular weight: 17004.59 Da        Isoelectric Point: 6.3405

>AT284844 WP_013973163.1 NZ_CP128542:c3746609-3746160 [Pseudomonas asiatica]
MLAEVLRDNGYHEYRARLHALLEIPELASDFEIHTRITHGFAATWLVKLTELGVFTPVERDQIIPLRTLKTRIERDQPLT
VEESDRLFRSAHITAMAEAVFGEAGKAKRWLSKPKERFSGLTPMQMLTTQQGTTQVEEMLLQIAEGFGL

Download         Length: 450 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A0C1HTG7

Antitoxin

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Source
ID
Structure
AlphaFold DBF8G488

References