Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | /RES-TIGR02293 |
| Location | 3745726..3746609 | Replicon | chromosome |
| Accession | NZ_CP128542 | ||
| Organism | Pseudomonas asiatica strain NMI3658_15 | ||
Toxin (Protein)
| Gene name | - | Uniprot ID | A0A0C1HTG7 |
| Locus tag | LU687_RS17780 | Protein ID | WP_015270851.1 |
| Coordinates | 3745726..3746163 (-) | Length | 146 a.a. |
Antitoxin (Protein)
| Gene name | - | Uniprot ID | F8G488 |
| Locus tag | LU687_RS17785 | Protein ID | WP_013973163.1 |
| Coordinates | 3746160..3746609 (-) | Length | 150 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LU687_RS17760 (LU687_017760) | 3740954..3742018 | + | 1065 | WP_015270847.1 | TerC family protein | - |
| LU687_RS17765 (LU687_017765) | 3742096..3743325 | - | 1230 | WP_015270848.1 | acyl-CoA dehydrogenase | - |
| LU687_RS17770 (LU687_017770) | 3743466..3744392 | + | 927 | WP_015270849.1 | LysR family transcriptional regulator | - |
| LU687_RS17775 (LU687_017775) | 3744564..3745718 | + | 1155 | WP_015270850.1 | aminotransferase class V-fold PLP-dependent enzyme | - |
| LU687_RS17780 (LU687_017780) | 3745726..3746163 | - | 438 | WP_015270851.1 | RES family NAD+ phosphorylase | Toxin |
| LU687_RS17785 (LU687_017785) | 3746160..3746609 | - | 450 | WP_013973163.1 | DUF2384 domain-containing protein | Antitoxin |
| LU687_RS17790 (LU687_017790) | 3746708..3747361 | - | 654 | WP_015270852.1 | oxygen-insensitive NAD(P)H-dependent nitroreductase NfsB | - |
| LU687_RS17795 (LU687_017795) | 3747466..3748389 | + | 924 | WP_015270853.1 | LysR family transcriptional regulator | - |
| LU687_RS17800 (LU687_017800) | 3748437..3749267 | + | 831 | WP_015270854.1 | AraC family transcriptional regulator | - |
| LU687_RS17805 (LU687_017805) | 3749318..3749902 | + | 585 | WP_015270855.1 | LysE family translocator | - |
| LU687_RS17810 (LU687_017810) | 3750042..3751241 | - | 1200 | WP_043935712.1 | sugar transporter | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 146 a.a. Molecular weight: 15969.19 Da Isoelectric Point: 5.1199
>T284844 WP_015270851.1 NZ_CP128542:c3746163-3745726 [Pseudomonas asiatica]
VILWRISAYADLSGTGGLRVSGRWHQAGRPVVYAATSPAGAMLEVLVHLEIDPEDFPTTMRLLRIELPDTVSQAQLPALQ
PGWSSQTELTRGLGNRFLDECSALLLPVPSAIMPSTTNYLFNPRHPQANSARLEVEDFTPDSRLF
VILWRISAYADLSGTGGLRVSGRWHQAGRPVVYAATSPAGAMLEVLVHLEIDPEDFPTTMRLLRIELPDTVSQAQLPALQ
PGWSSQTELTRGLGNRFLDECSALLLPVPSAIMPSTTNYLFNPRHPQANSARLEVEDFTPDSRLF
Download Length: 438 bp
Antitoxin
Download Length: 150 a.a. Molecular weight: 17004.59 Da Isoelectric Point: 6.3405
>AT284844 WP_013973163.1 NZ_CP128542:c3746609-3746160 [Pseudomonas asiatica]
MLAEVLRDNGYHEYRARLHALLEIPELASDFEIHTRITHGFAATWLVKLTELGVFTPVERDQIIPLRTLKTRIERDQPLT
VEESDRLFRSAHITAMAEAVFGEAGKAKRWLSKPKERFSGLTPMQMLTTQQGTTQVEEMLLQIAEGFGL
MLAEVLRDNGYHEYRARLHALLEIPELASDFEIHTRITHGFAATWLVKLTELGVFTPVERDQIIPLRTLKTRIERDQPLT
VEESDRLFRSAHITAMAEAVFGEAGKAKRWLSKPKERFSGLTPMQMLTTQQGTTQVEEMLLQIAEGFGL
Download Length: 450 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A0C1HTG7 |
Antitoxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | F8G488 |