Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 2501309..2501825 Replicon chromosome
Accession NZ_CP128542
Organism Pseudomonas asiatica strain NMI3658_15

Toxin (Protein)


Gene name relE Uniprot ID F8G1E7
Locus tag LU687_RS12235 Protein ID WP_003259987.1
Coordinates 2501544..2501825 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID F8G1E6
Locus tag LU687_RS12230 Protein ID WP_013972043.1
Coordinates 2501309..2501554 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LU687_RS12210 (LU687_012210) 2496721..2497200 - 480 WP_015269934.1 transposase -
LU687_RS12215 (LU687_012215) 2497457..2497999 - 543 WP_015269935.1 WYL domain-containing protein -
LU687_RS12220 (LU687_012220) 2498735..2499928 + 1194 WP_015269936.1 MFS transporter -
LU687_RS12225 (LU687_012225) 2499959..2501065 + 1107 WP_015269937.1 alkene reductase -
LU687_RS12230 (LU687_012230) 2501309..2501554 + 246 WP_013972043.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
LU687_RS12235 (LU687_012235) 2501544..2501825 + 282 WP_003259987.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LU687_RS12240 (LU687_012240) 2501841..2502473 - 633 WP_015269938.1 BRCT domain-containing protein -
LU687_RS12245 (LU687_012245) 2502490..2502885 - 396 WP_023662326.1 hypothetical protein -
LU687_RS12250 (LU687_012250) 2502974..2503882 - 909 WP_015269940.1 LysR family transcriptional regulator -
LU687_RS12255 (LU687_012255) 2504174..2505478 + 1305 WP_013972046.1 MFS transporter -
LU687_RS12260 (LU687_012260) 2505509..2506750 + 1242 WP_015269941.1 Zn-dependent hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(10-76)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10909.78 Da        Isoelectric Point: 10.7594

>T284843 WP_003259987.1 NZ_CP128542:2501544-2501825 [Pseudomonas asiatica]
MTYKLEFLPSALKEWGKLGHTVREQIKKKLAERLQSPKVQADALRDLPNHYKIKLKASGYRLVYRVEDERIVVVVVSVGK
RERSEVYRSAQKR

Download         Length: 282 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8779.21 Da        Isoelectric Point: 4.3611

>AT284843 WP_013972043.1 NZ_CP128542:2501309-2501554 [Pseudomonas asiatica]
MQNIFADVAVSVSELKKNPSAVMTGAAGMPVAVLNHNRVMGYMVPAELYEAMMERLEDLELSELAKSRLGEKGVPVSLDD
L

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB F8G1E7

Antitoxin

Source ID Structure
AlphaFold DB F8G1E6

References