Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 994270..994856 Replicon chromosome
Accession NZ_CP128542
Organism Pseudomonas asiatica strain NMI3658_15

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag LU687_RS04650 Protein ID WP_080604915.1
Coordinates 994270..994563 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID A0A2N5BNF2
Locus tag LU687_RS04655 Protein ID WP_061303299.1
Coordinates 994560..994856 (+) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LU687_RS04625 (LU687_004625) 989762..990616 + 855 WP_015269000.1 putative selenate ABC transporter substrate-binding protein -
LU687_RS04630 (LU687_004630) 990637..991431 + 795 WP_015269001.1 phosphonate ABC transporter ATP-binding protein -
LU687_RS04635 (LU687_004635) 991425..992252 + 828 WP_015269002.1 ABC transporter permease -
LU687_RS04640 (LU687_004640) 992249..993016 + 768 WP_015269003.1 phosphonate ABC transporter, permease protein PhnE -
LU687_RS04645 (LU687_004645) 993156..994049 - 894 WP_015269004.1 bestrophin family ion channel -
LU687_RS04650 (LU687_004650) 994270..994563 + 294 WP_080604915.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LU687_RS04655 (LU687_004655) 994560..994856 + 297 WP_061303299.1 putative addiction module antidote protein Antitoxin
LU687_RS04660 (LU687_004660) 995010..995912 - 903 WP_015269007.1 transporter substrate-binding domain-containing protein -
LU687_RS04665 (LU687_004665) 995940..997256 - 1317 WP_223998113.1 D-amino acid dehydrogenase -
LU687_RS04670 (LU687_004670) 997319..998224 + 906 WP_015269009.1 LysR substrate-binding domain-containing protein -
LU687_RS04680 (LU687_004680) 998466..999515 + 1050 WP_013971008.1 tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(22-86)

Antitoxin

Uncharacterized protein HI1420

(4-92)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10793.69 Da        Isoelectric Point: 10.5815

>T284842 WP_080604915.1 NZ_CP128542:994270-994563 [Pseudomonas asiatica]
MYLVEQTESFAVWLSSLRDLRAQLAIGRRLERAAMGNLGDVKWLGGGIGELRIDVAAGYRVYFAQKGQRLVLLLVGGDKS
TQATDILKARKLLKEMK

Download         Length: 294 bp

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 10658.38 Da        Isoelectric Point: 6.4669

>AT284842 WP_061303299.1 NZ_CP128542:994560-994856 [Pseudomonas asiatica]
MSEKLIPFDMAALLSSDEAITEYLSQVLADGDTEEIIRALGHIARARGMTRIATESGLGRESLYKALSPGAKPRFDTVLK
VIRALGVDLLVQPHVVPR

Download         Length: 297 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A2N5BNF2

References