Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | PP_4151-4152/excise(antitoxin) |
Location | 2040376..2041415 | Replicon | chromosome |
Accession | NZ_CP128540 | ||
Organism | Pseudomonas alloputida strain NMI24_14 |
Toxin (Protein)
Gene name | PP_4152 | Uniprot ID | Q88FE5 |
Locus tag | LU682_RS09345 | Protein ID | WP_010954922.1 |
Coordinates | 2040376..2040951 (-) | Length | 192 a.a. |
Antitoxin (Protein)
Gene name | PP_4151 | Uniprot ID | A0A2V4F8J0 |
Locus tag | LU682_RS09350 | Protein ID | WP_049588231.1 |
Coordinates | 2040948..2041415 (-) | Length | 156 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
LU682_RS09335 (LU682_009335) | 2036005..2037228 | + | 1224 | WP_010954925.1 | NAD(P)/FAD-dependent oxidoreductase | - |
LU682_RS09340 (LU682_009340) | 2037232..2040162 | - | 2931 | WP_049588229.1 | aminotransferase | - |
LU682_RS09345 (LU682_009345) | 2040376..2040951 | - | 576 | WP_010954922.1 | PIN domain-containing protein | Toxin |
LU682_RS09350 (LU682_009350) | 2040948..2041415 | - | 468 | WP_049588231.1 | helix-turn-helix domain-containing protein | Antitoxin |
LU682_RS09355 (LU682_009355) | 2041563..2043167 | - | 1605 | WP_010954920.1 | ABC transporter ATP-binding protein | - |
LU682_RS09360 (LU682_009360) | 2043169..2044188 | - | 1020 | WP_010954919.1 | ABC transporter permease | - |
LU682_RS09365 (LU682_009365) | 2044190..2045263 | - | 1074 | WP_010954918.1 | microcin C ABC transporter permease YejB | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 192 a.a. Molecular weight: 21646.86 Da Isoelectric Point: 5.5710
>T284834 WP_010954922.1 NZ_CP128540:c2040951-2040376 [Pseudomonas alloputida]
MKHSPFTAIYDANVLYPAPLRDFLMNLALTGIYRARWSASIHDEWKRNLLLNRPDLTPEHLDRTSSLMDAAVPDALVTDY
DSLVEGLDLPDRDDRHVLAAAIKCNASVIVTFNLKDFSKAVLGAFDIEPLHPDDFIADLWDLDKAAVLEAAQRQRISLKN
PPHSVQQYLDRLLQQKLPETVKLLSAFKFLL
MKHSPFTAIYDANVLYPAPLRDFLMNLALTGIYRARWSASIHDEWKRNLLLNRPDLTPEHLDRTSSLMDAAVPDALVTDY
DSLVEGLDLPDRDDRHVLAAAIKCNASVIVTFNLKDFSKAVLGAFDIEPLHPDDFIADLWDLDKAAVLEAAQRQRISLKN
PPHSVQQYLDRLLQQKLPETVKLLSAFKFLL
Download Length: 576 bp
Antitoxin
Download Length: 156 a.a. Molecular weight: 17112.54 Da Isoelectric Point: 6.3403
>AT284834 WP_049588231.1 NZ_CP128540:c2041415-2040948 [Pseudomonas alloputida]
MTTANLSSHVLPDEKEIAVAVESSRTLAAFLSTKSDTQRIELLNEENQRQVVEVPTFALRLFGEILSELALGNSVKVVPI
HAELTTQEAADLLNVSRPHLVKLLDEAVIPHTKTGRHRRVKFSDLVAYKDKRDGVSRAAIDALAAQAQELKMGYE
MTTANLSSHVLPDEKEIAVAVESSRTLAAFLSTKSDTQRIELLNEENQRQVVEVPTFALRLFGEILSELALGNSVKVVPI
HAELTTQEAADLLNVSRPHLVKLLDEAVIPHTKTGRHRRVKFSDLVAYKDKRDGVSRAAIDALAAQAQELKMGYE
Download Length: 468 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | Q88FE5 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A2V4F8J0 |