Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | PP_4151-4152/excise(antitoxin) |
| Location | 4426026..4427065 | Replicon | chromosome |
| Accession | NC_019670 | ||
| Organism | Pseudomonas sp. UW4 | ||
Toxin (Protein)
| Gene name | PP_4152 | Uniprot ID | - |
| Locus tag | PPUTUW4_RS19445 | Protein ID | WP_015096212.1 |
| Coordinates | 4426490..4427065 (+) | Length | 192 a.a. |
Antitoxin (Protein)
| Gene name | PP_4151 | Uniprot ID | K9NP50 |
| Locus tag | PPUTUW4_RS19440 | Protein ID | WP_015096211.1 |
| Coordinates | 4426026..4426493 (+) | Length | 156 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| PPUTUW4_RS19420 | 4421559..4422473 | + | 915 | WP_015096207.1 | urea transporter | - |
| PPUTUW4_RS19425 | 4422495..4423319 | + | 825 | WP_015096208.1 | ion transporter | - |
| PPUTUW4_RS19430 | 4423413..4424408 | + | 996 | WP_015096209.1 | sulfate ABC transporter substrate-binding protein | - |
| PPUTUW4_RS19435 | 4424654..4425859 | + | 1206 | WP_015096210.1 | MFS transporter | - |
| PPUTUW4_RS19440 | 4426026..4426493 | + | 468 | WP_015096211.1 | helix-turn-helix domain-containing protein | Antitoxin |
| PPUTUW4_RS19445 | 4426490..4427065 | + | 576 | WP_015096212.1 | PIN domain-containing protein | Toxin |
| PPUTUW4_RS29945 | 4427023..4427172 | - | 150 | WP_158467558.1 | hypothetical protein | - |
| PPUTUW4_RS19450 | 4427163..4427729 | - | 567 | WP_015096213.1 | phosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN | - |
| PPUTUW4_RS28345 | 4428546..4428953 | - | 408 | WP_015096214.1 | hypothetical protein | - |
| PPUTUW4_RS19455 | 4428968..4430170 | - | 1203 | WP_015096215.1 | c-type cytochrome biogenesis protein CcmI | - |
| PPUTUW4_RS19460 | 4430163..4430636 | - | 474 | WP_015096216.1 | cytochrome c-type biogenesis protein CcmH | - |
| PPUTUW4_RS19465 | 4430633..4431169 | - | 537 | WP_015096217.1 | DsbE family thiol:disulfide interchange protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 192 a.a. Molecular weight: 21422.68 Da Isoelectric Point: 7.2645
>T28480 WP_015096212.1 NC_019670:4426490-4427065 [Pseudomonas sp. UW4]
VRHSSFTAVYDACVLYPAPLRDFLMWLALSGLFRAKWSVAIHDEWKRNLLKNRPDLNATQLNRTCELMDLAIPDACVSGY
EALIQGLTLPDANDRHVLAAAIRCNASVIVTFNQKDFPRTALQPYGIEAQHPDEFVNDLFDLDPAAVVAAAQRQRKQLKA
PPMNSDTYLDLLLRQGLVQSVKALNSFRAML
VRHSSFTAVYDACVLYPAPLRDFLMWLALSGLFRAKWSVAIHDEWKRNLLKNRPDLNATQLNRTCELMDLAIPDACVSGY
EALIQGLTLPDANDRHVLAAAIRCNASVIVTFNQKDFPRTALQPYGIEAQHPDEFVNDLFDLDPAAVVAAAQRQRKQLKA
PPMNSDTYLDLLLRQGLVQSVKALNSFRAML
Download Length: 576 bp
>T28480 NC_019670:4426490-4427065 [Pseudomonas sp. UW4]
GTGAGGCACTCTTCATTTACCGCTGTATATGACGCTTGCGTGCTTTACCCCGCGCCCTTGAGAGACTTTCTGATGTGGCT
AGCGCTCTCCGGGCTTTTCAGGGCGAAATGGTCAGTGGCAATACACGATGAATGGAAACGCAATCTGCTGAAAAACCGCC
CGGATCTCAACGCCACGCAATTGAATCGCACCTGCGAGCTAATGGATCTGGCGATTCCCGACGCCTGCGTGTCGGGGTAC
GAAGCCTTGATACAGGGACTGACGCTGCCCGATGCGAATGACCGACATGTCCTGGCGGCTGCCATTCGTTGCAACGCCAG
CGTCATTGTCACCTTCAACCAGAAAGACTTCCCCCGCACCGCGCTGCAACCTTATGGCATCGAGGCCCAGCACCCCGACG
AATTCGTCAATGACCTTTTCGACCTGGATCCGGCAGCAGTGGTCGCCGCGGCACAACGACAGCGCAAGCAACTGAAGGCC
CCACCGATGAACAGTGACACTTATCTCGATCTATTGTTACGTCAAGGCCTGGTTCAGTCGGTCAAGGCATTGAACAGTTT
CCGGGCAATGCTTTGA
GTGAGGCACTCTTCATTTACCGCTGTATATGACGCTTGCGTGCTTTACCCCGCGCCCTTGAGAGACTTTCTGATGTGGCT
AGCGCTCTCCGGGCTTTTCAGGGCGAAATGGTCAGTGGCAATACACGATGAATGGAAACGCAATCTGCTGAAAAACCGCC
CGGATCTCAACGCCACGCAATTGAATCGCACCTGCGAGCTAATGGATCTGGCGATTCCCGACGCCTGCGTGTCGGGGTAC
GAAGCCTTGATACAGGGACTGACGCTGCCCGATGCGAATGACCGACATGTCCTGGCGGCTGCCATTCGTTGCAACGCCAG
CGTCATTGTCACCTTCAACCAGAAAGACTTCCCCCGCACCGCGCTGCAACCTTATGGCATCGAGGCCCAGCACCCCGACG
AATTCGTCAATGACCTTTTCGACCTGGATCCGGCAGCAGTGGTCGCCGCGGCACAACGACAGCGCAAGCAACTGAAGGCC
CCACCGATGAACAGTGACACTTATCTCGATCTATTGTTACGTCAAGGCCTGGTTCAGTCGGTCAAGGCATTGAACAGTTT
CCGGGCAATGCTTTGA
Antitoxin
Download Length: 156 a.a. Molecular weight: 17354.82 Da Isoelectric Point: 6.4953
>AT28480 WP_015096211.1 NC_019670:4426026-4426493 [Pseudomonas sp. UW4]
MSTVIHPPINLPAKHEIQAAIEGQRTLAAYLATQFETQHIQIFDEQNEAHNIELPTSALRLLVDILAELAAGNAVKVVPI
HAELTTQEAADLLNVSRPHLIKLLESGELSYHKTGKHRRVRFADLMNYKNRRDTASEQAMMLLAEQAQALRTGYE
MSTVIHPPINLPAKHEIQAAIEGQRTLAAYLATQFETQHIQIFDEQNEAHNIELPTSALRLLVDILAELAAGNAVKVVPI
HAELTTQEAADLLNVSRPHLIKLLESGELSYHKTGKHRRVRFADLMNYKNRRDTASEQAMMLLAEQAQALRTGYE
Download Length: 468 bp
>AT28480 NC_019670:4426026-4426493 [Pseudomonas sp. UW4]
ATGTCGACCGTCATCCATCCGCCAATCAATTTGCCCGCGAAACACGAAATACAGGCCGCAATCGAGGGGCAACGCACCCT
GGCTGCCTATCTCGCCACCCAGTTCGAAACTCAGCATATCCAGATATTCGATGAGCAGAACGAAGCGCATAACATCGAAC
TGCCCACCTCGGCGCTCCGTTTGCTAGTCGATATTCTGGCGGAACTCGCAGCCGGTAACGCTGTGAAAGTAGTCCCGATT
CACGCTGAACTGACTACGCAAGAAGCGGCAGACCTGCTCAATGTCTCACGTCCACACCTGATCAAACTGCTCGAATCCGG
CGAACTGTCCTACCACAAAACCGGCAAGCACCGACGTGTGCGTTTTGCCGATTTGATGAACTATAAAAACCGGCGCGACA
CCGCCAGCGAGCAGGCAATGATGCTTCTCGCCGAGCAGGCACAGGCGTTAAGGACAGGATACGAGTGA
ATGTCGACCGTCATCCATCCGCCAATCAATTTGCCCGCGAAACACGAAATACAGGCCGCAATCGAGGGGCAACGCACCCT
GGCTGCCTATCTCGCCACCCAGTTCGAAACTCAGCATATCCAGATATTCGATGAGCAGAACGAAGCGCATAACATCGAAC
TGCCCACCTCGGCGCTCCGTTTGCTAGTCGATATTCTGGCGGAACTCGCAGCCGGTAACGCTGTGAAAGTAGTCCCGATT
CACGCTGAACTGACTACGCAAGAAGCGGCAGACCTGCTCAATGTCTCACGTCCACACCTGATCAAACTGCTCGAATCCGG
CGAACTGTCCTACCACAAAACCGGCAAGCACCGACGTGTGCGTTTTGCCGATTTGATGAACTATAAAAACCGGCGCGACA
CCGCCAGCGAGCAGGCAATGATGCTTCTCGCCGAGCAGGCACAGGCGTTAAGGACAGGATACGAGTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|