Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relB-yefM/YoeB-RelB
Location 3871847..3872354 Replicon chromosome
Accession NC_019427
Organism Anabaena sp. 90

Toxin (Protein)


Gene name relB Uniprot ID K7WKJ2
Locus tag ANA_RS16730 Protein ID WP_015081215.1
Coordinates 3872094..3872354 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID K7W546
Locus tag ANA_RS16725 Protein ID WP_015081214.1
Coordinates 3871847..3872101 (+) Length 85 a.a.

Genomic Context


ANA_RS16700ANA_RS16725ANA_RS16730ANA_RS23685ANA_RS23690ANA_RS26680ANA_RS16705ANA_RS16710ANA_RS16715ANA_RS16720ANA_RS23680
Location: 3867009..3867668 (660 bp)
Type: Others
Protein ID: WP_015081209.1
Location: 3871847..3872101 (255 bp)
Type: Antitoxin
Protein ID: WP_015081214.1
Location: 3872094..3872354 (261 bp)
Type: Toxin
Protein ID: WP_015081215.1
Location: 3874822..3875130 (309 bp)
Type: Others
Protein ID: WP_148279069.1
Location: 3875171..3875776 (606 bp)
Type: Others
Protein ID: WP_051155210.1
Location: 3866851..3867003 (153 bp)
Type: Others
Protein ID: WP_158310548.1
Location: 3867850..3868326 (477 bp)
Type: Others
Protein ID: WP_015081210.1
Location: 3869658..3870914 (1257 bp)
Type: Others
Protein ID: WP_015081211.1
Location: 3870976..3871374 (399 bp)
Type: Others
Protein ID: WP_015081212.1
Location: 3871371..3871670 (300 bp)
Type: Others
Protein ID: WP_015081213.1
Location: 3872881..3874500 (1620 bp)
Type: Others
Protein ID: WP_015081216.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
ANA_RS266803866851..3867003-153WP_158310548.1hypothetical protein-
ANA_RS167003867009..3867668+660WP_015081209.1rhomboid family intramembrane serine protease-
ANA_RS167053867850..3868326-477WP_015081210.1DUF1499 domain-containing protein-
ANA_RS167103869658..3870914-1257WP_015081211.1glycosyltransferase family 4 protein-
ANA_RS167153870976..3871374-399WP_015081212.1hypothetical protein-
ANA_RS167203871371..3871670-300WP_015081213.1hypothetical protein-
ANA_RS167253871847..3872101+255WP_015081214.1type II toxin-antitoxin system prevent-host-death family antitoxinAntitoxin
ANA_RS167303872094..3872354+261WP_015081215.1Txe/YoeB family addiction module toxinToxin
ANA_RS236803872881..3874500-1620WP_015081216.1calcium-binding protein-
ANA_RS236853874822..3875130+309WP_148279069.1helix-turn-helix domain-containing protein-
ANA_RS236903875171..3875776+606WP_051155210.1AAA family ATPase-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(7-86)

Antitoxin

(1-74)


Sequences


Toxin        


Download         Length: 87 a.a.        Molecular weight: 10336.83 Da        Isoelectric Point: 6.9752

>T28471 WP_015081215.1 NC_019427:3872094-3872354 [Anabaena sp. 90]
MSRMLAWTDEAWGNYLYWQGQDQKTLKRINKLIEETMRMPFEGIGKPEPLKENLAGFWSRRIDDTNRLVYAVDDVYVTII
SCRYHY

Download         Length: 261 bp

>T28471 NC_019427:3872094-3872354 [Anabaena sp. 90]
ATGAGTAGAATGTTGGCTTGGACTGATGAGGCTTGGGGTAATTATCTTTACTGGCAAGGGCAAGATCAAAAGACTCTCAA
AAGAATCAATAAGTTGATTGAGGAAACGATGCGGATGCCTTTTGAGGGTATTGGTAAACCAGAGCCTCTCAAGGAAAATT
TAGCCGGATTTTGGTCACGGCGAATTGATGATACAAATCGTTTGGTTTATGCTGTTGATGATGTCTATGTAACTATTATT
TCTTGCCGATATCATTATTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9496.84 Da        Isoelectric Point: 5.6558

>AT28471 WP_015081214.1 NC_019427:3871847-3872101 [Anabaena sp. 90]
MKIISFSEARNSLKTVLDQVTADADYTIITRRDADDTVVMSLEFFNSLMETVHLLKSPANAAHLERSIAQFKQGKVVQRD
LLNE

Download         Length: 255 bp

>AT28471 NC_019427:3871847-3872101 [Anabaena sp. 90]
ATGAAAATTATCTCTTTTAGCGAGGCCAGAAATAGTCTGAAAACGGTTTTAGACCAGGTGACGGCAGATGCCGACTATAC
AATTATCACTAGACGGGATGCTGATGATACGGTGGTGATGTCCCTGGAGTTTTTTAATAGTCTCATGGAGACTGTGCATT
TATTGAAGTCTCCGGCAAATGCAGCCCATTTAGAACGTTCCATTGCTCAATTTAAGCAGGGGAAGGTGGTGCAGCGAGAT
TTGTTAAATGAGTAG

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
AlphaFold DBA0A844IIX7


Antitoxin

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Source
ID
Structure
AlphaFold DBA0A844IL67

References