Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 3638248..3639131 Replicon chromosome
Accession NZ_CP128508
Organism Pseudomonas asiatica strain F19-1

Toxin (Protein)


Gene name - Uniprot ID A0A0C1HTG7
Locus tag QUC26_RS16910 Protein ID WP_015270851.1
Coordinates 3638248..3638685 (-) Length 146 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag QUC26_RS16915 Protein ID WP_274298142.1
Coordinates 3638682..3639131 (-) Length 150 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QUC26_RS16895 (QUC26_16895) 3634618..3635847 - 1230 WP_013973159.1 acyl-CoA dehydrogenase -
QUC26_RS16900 (QUC26_16900) 3635988..3636914 + 927 WP_013973160.1 LysR family transcriptional regulator -
QUC26_RS16905 (QUC26_16905) 3637086..3638240 + 1155 WP_013973161.1 aminotransferase class V-fold PLP-dependent enzyme -
QUC26_RS16910 (QUC26_16910) 3638248..3638685 - 438 WP_015270851.1 RES family NAD+ phosphorylase Toxin
QUC26_RS16915 (QUC26_16915) 3638682..3639131 - 450 WP_274298142.1 DUF2384 domain-containing protein Antitoxin
QUC26_RS16920 (QUC26_16920) 3639230..3639883 - 654 WP_013973164.1 oxygen-insensitive NAD(P)H-dependent nitroreductase NfsB -
QUC26_RS16925 (QUC26_16925) 3639988..3640911 + 924 WP_013973165.1 LysR family transcriptional regulator -
QUC26_RS16930 (QUC26_16930) 3640959..3641789 + 831 WP_013973166.1 AraC family transcriptional regulator -
QUC26_RS16935 (QUC26_16935) 3641840..3642424 + 585 WP_013973167.1 LysE family translocator -
QUC26_RS16940 (QUC26_16940) 3642545..3643762 - 1218 WP_044047087.1 sugar transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(3-137)

Antitoxin

Antitoxin Xre-like, helix-turn-helix domain

(33-91)


Sequences

Toxin        


Download         Length: 146 a.a.        Molecular weight: 15969.19 Da        Isoelectric Point: 5.1199

>T284684 WP_015270851.1 NZ_CP128508:c3638685-3638248 [Pseudomonas asiatica]
VILWRISAYADLSGTGGLRVSGRWHQAGRPVVYAATSPAGAMLEVLVHLEIDPEDFPTTMRLLRIELPDTVSQAQLPALQ
PGWSSQTELTRGLGNRFLDECSALLLPVPSAIMPSTTNYLFNPRHPQANSARLEVEDFTPDSRLF

Download         Length: 438 bp

Antitoxin


Download         Length: 150 a.a.        Molecular weight: 17032.64 Da        Isoelectric Point: 6.3405

>AT284684 WP_274298142.1 NZ_CP128508:c3639131-3638682 [Pseudomonas asiatica]
MLAEVLRDNGYHEYRARLHALLEIPELASDFEIHTRITHGFAATWLVKLTELGVFTPVERDQIIPLRTLKTRIERDQPLT
VEESDRLFRSAHITAMAEAVFGEVGKAKRWLSKPKERFSGLTPMQMLTTQQGTTQVEEMLLQIAEGFGL

Download         Length: 450 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C1HTG7

Antitoxin

Source ID Structure

References