Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 2430457..2430973 Replicon chromosome
Accession NZ_CP128508
Organism Pseudomonas asiatica strain F19-1

Toxin (Protein)


Gene name relE Uniprot ID F8G1E7
Locus tag QUC26_RS11310 Protein ID WP_003259987.1
Coordinates 2430692..2430973 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag QUC26_RS11305 Protein ID WP_096010237.1
Coordinates 2430457..2430702 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QUC26_RS11285 (QUC26_11285) 2425884..2426426 - 543 WP_013972039.1 WYL domain-containing protein -
QUC26_RS11290 (QUC26_11290) 2426534..2427520 - 987 WP_013972040.1 zinc-binding dehydrogenase -
QUC26_RS11295 (QUC26_11295) 2427883..2429076 + 1194 WP_025338595.1 MFS transporter -
QUC26_RS11300 (QUC26_11300) 2429107..2430213 + 1107 WP_096010236.1 alkene reductase -
QUC26_RS11305 (QUC26_11305) 2430457..2430702 + 246 WP_096010237.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
QUC26_RS11310 (QUC26_11310) 2430692..2430973 + 282 WP_003259987.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QUC26_RS11315 (QUC26_11315) 2431012..2431407 - 396 WP_023662326.1 hypothetical protein -
QUC26_RS11320 (QUC26_11320) 2431496..2432404 - 909 WP_096010238.1 LysR family transcriptional regulator -
QUC26_RS11325 (QUC26_11325) 2432694..2433998 + 1305 WP_013972046.1 MFS transporter -
QUC26_RS11330 (QUC26_11330) 2434029..2435270 + 1242 WP_013972047.1 Zn-dependent hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(10-76)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10909.78 Da        Isoelectric Point: 10.7594

>T284683 WP_003259987.1 NZ_CP128508:2430692-2430973 [Pseudomonas asiatica]
MTYKLEFLPSALKEWGKLGHTVREQIKKKLAERLQSPKVQADALRDLPNHYKIKLKASGYRLVYRVEDERIVVVVVSVGK
RERSEVYRSAQKR

Download         Length: 282 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8749.18 Da        Isoelectric Point: 4.3611

>AT284683 WP_096010237.1 NZ_CP128508:2430457-2430702 [Pseudomonas asiatica]
MQNIFADVAVSVSELKKNPSAVMTGAAGMPVAVLNHNRVMGYMVPAELYEAMMERLEDLELGELAKSRLGEKGVPVSLDD
L

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB F8G1E7

Antitoxin

Source ID Structure

References