284682

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/RHH(antitoxin)
Location 2400889..2401442 Replicon chromosome
Accession NZ_CP128508
Organism Pseudomonas asiatica strain F19-1

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag QUC26_RS11145 Protein ID WP_003155924.1
Coordinates 2401149..2401442 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A431XAN4
Locus tag QUC26_RS11140 Protein ID WP_003155922.1
Coordinates 2400889..2401161 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QUC26_RS11135 (QUC26_11135) 2400520..2400765 + 246 Protein_2160 type II toxin-antitoxin system Phd/YefM family antitoxin -
QUC26_RS11140 (QUC26_11140) 2400889..2401161 + 273 WP_003155922.1 CopG family ribbon-helix-helix protein Antitoxin
QUC26_RS11145 (QUC26_11145) 2401149..2401442 + 294 WP_003155924.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QUC26_RS11150 (QUC26_11150) 2401436..2402479 - 1044 Protein_2163 site-specific integrase -
QUC26_RS11155 (QUC26_11155) 2402442..2402951 + 510 Protein_2164 IS5 family transposase -
QUC26_RS11160 (QUC26_11160) 2403473..2404726 + 1254 WP_104963084.1 group II intron reverse transcriptase/maturase -
QUC26_RS11165 (QUC26_11165) 2404800..2405270 + 471 Protein_2166 IS5 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-95)

Antitoxin

Ribbon-helix-helix protein, CopG

(3-40)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11213.69 Da        Isoelectric Point: 5.9081

>T284682 WP_003155924.1 NZ_CP128508:2401149-2401442 [Pseudomonas asiatica]
VPRLIVTEGAAKGLERCRRFLSDKDPQVARRAAQAIERQFVRLEESPEVGRPFPDLPELRELIIEFGDSGYVALYRYERA
DDTTYVLAFRHQKEAGY

Download         Length: 294 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10369.53 Da        Isoelectric Point: 6.0804

>AT284682 WP_003155922.1 NZ_CP128508:2400889-2401161 [Pseudomonas asiatica]
MATSIKIDDELKGRIQHLAGLRQRSSHWIMREAITQYVEREEARESFKQEALASWAAYQETGRHLTGQEARTWLGSWGTD
AEAELPKCHD

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A431XAN4

References