Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/- |
| Location | 3524552..3525773 | Replicon | chromosome |
| Accession | NZ_CP128505 | ||
| Organism | Pseudomonas aeruginosa strain Fe8-1 | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | - |
| Locus tag | QUC25_RS16200 | Protein ID | WP_003114949.1 |
| Coordinates | 3525195..3525773 (+) | Length | 193 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | - |
| Locus tag | QUC25_RS16195 | Protein ID | WP_003088112.1 |
| Coordinates | 3524552..3525106 (+) | Length | 185 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QUC25_RS16170 (QUC25_16170) | 3520120..3520671 | + | 552 | WP_003102727.1 | XRE family transcriptional regulator | - |
| QUC25_RS16175 (QUC25_16175) | 3520668..3521066 | - | 399 | WP_003088123.1 | NADH-quinone oxidoreductase subunit A | - |
| QUC25_RS16180 (QUC25_16180) | 3521079..3521402 | - | 324 | WP_003102734.1 | multidrug efflux SMR transporter | - |
| QUC25_RS16185 (QUC25_16185) | 3521733..3522194 | + | 462 | WP_003102736.1 | (2Fe-2S)-binding protein | - |
| QUC25_RS16190 (QUC25_16190) | 3522199..3524394 | + | 2196 | WP_289344294.1 | xanthine dehydrogenase family protein molybdopterin-binding subunit | - |
| QUC25_RS16195 (QUC25_16195) | 3524552..3525106 | + | 555 | WP_003088112.1 | helix-turn-helix transcriptional regulator | Antitoxin |
| QUC25_RS16200 (QUC25_16200) | 3525195..3525773 | + | 579 | WP_003114949.1 | HD domain-containing protein | Toxin |
| QUC25_RS16205 (QUC25_16205) | 3525882..3527069 | - | 1188 | WP_003139884.1 | HlyD family efflux transporter periplasmic adaptor subunit | - |
| QUC25_RS16210 (QUC25_16210) | 3527059..3529230 | - | 2172 | WP_003139887.1 | type I secretion system permease/ATPase | - |
| QUC25_RS16215 (QUC25_16215) | 3529220..3530497 | - | 1278 | WP_003088104.1 | TolC family protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 193 a.a. Molecular weight: 21897.75 Da Isoelectric Point: 5.3655
>T284667 WP_003114949.1 NZ_CP128505:3525195-3525773 [Pseudomonas aeruginosa]
MSLELLSNRLEFLREAERLKDVLRSAHTSSGRPESTAEHSWRLCLMALAFEDQLAGLDLGKVLRMCVVHDLGEAIHGDIP
AVEQAAHPDKGEQERADLLQLTRHLDAPLRDRLLALWDEYERGESAEALAVKALDKLETLLQHTQGDNPADFDYAFNLDY
GRRYTDRAPLFKTLRELLDARTRQRLAVRRDA
MSLELLSNRLEFLREAERLKDVLRSAHTSSGRPESTAEHSWRLCLMALAFEDQLAGLDLGKVLRMCVVHDLGEAIHGDIP
AVEQAAHPDKGEQERADLLQLTRHLDAPLRDRLLALWDEYERGESAEALAVKALDKLETLLQHTQGDNPADFDYAFNLDY
GRRYTDRAPLFKTLRELLDARTRQRLAVRRDA
Download Length: 579 bp
Antitoxin
Download Length: 185 a.a. Molecular weight: 20454.63 Da Isoelectric Point: 8.1590
>AT284667 WP_003088112.1 NZ_CP128505:3524552-3525106 [Pseudomonas aeruginosa]
MTEPLPSSSLGPALRRWRLLHRVKQTHAAELLGVAQSTISRWESGTQALLVEERARLERLLGARLEAAADQALARLVEAN
PQPVHLICDLTHRLLACSPARAAQFGVPLGELLDRSLWPYCSEEILRQEATLEELGWRELLAPPALEFASGANASAIVPI
RRSRCRWTRMTLSDGRAVRLVETL
MTEPLPSSSLGPALRRWRLLHRVKQTHAAELLGVAQSTISRWESGTQALLVEERARLERLLGARLEAAADQALARLVEAN
PQPVHLICDLTHRLLACSPARAAQFGVPLGELLDRSLWPYCSEEILRQEATLEELGWRELLAPPALEFASGANASAIVPI
RRSRCRWTRMTLSDGRAVRLVETL
Download Length: 555 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|