284663

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) spoIISABC/SpoIISA-SpoIISB
Location 2720047..2720964 Replicon chromosome
Accession NZ_CP128504
Organism Bacillus velezensis strain SRCM123434

Toxin (Protein)


Gene name spoIISA Uniprot ID -
Locus tag QTN49_RS13280 Protein ID WP_263611996.1
Coordinates 2720047..2720793 (+) Length 249 a.a.

Antitoxin (Protein)


Gene name spoIISB Uniprot ID I2HQ14
Locus tag QTN49_RS13285 Protein ID WP_003154807.1
Coordinates 2720794..2720964 (+) Length 57 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QTN49_RS13260 (2715441) 2715441..2716391 - 951 WP_007610844.1 ring-cleaving dioxygenase -
QTN49_RS13265 (2716713) 2716713..2718029 + 1317 WP_007610842.1 amino acid permease -
QTN49_RS13270 (2718315) 2718315..2718932 + 618 WP_003154804.1 DUF47 domain-containing protein -
QTN49_RS13275 (2718945) 2718945..2719943 + 999 WP_017417610.1 inorganic phosphate transporter -
QTN49_RS13280 (2720047) 2720047..2720793 + 747 WP_263611996.1 type II toxin-antitoxin system SpoIISA family toxin Toxin
QTN49_RS13285 (2720794) 2720794..2720964 + 171 WP_003154807.1 type II toxin-antitoxin system SpoIISB family antitoxin Antitoxin
QTN49_RS13290 (2721061) 2721061..2721186 + 126 WP_003154809.1 hypothetical protein -
QTN49_RS13295 (2721221) 2721221..2722099 - 879 WP_007407257.1 N-acetylmuramoyl-L-alanine amidase -
QTN49_RS13300 (2722113) 2722113..2722376 - 264 WP_003154813.1 phage holin -
QTN49_RS13305 (2722390) 2722390..2722653 - 264 WP_003154815.1 hemolysin XhlA family protein -
QTN49_RS13310 (2722704) 2722704..2723465 - 762 WP_017417609.1 hypothetical protein -
QTN49_RS13315 (2723522) 2723522..2723719 - 198 WP_007610833.1 XkdX family protein -
QTN49_RS13320 (2723724) 2723724..2724095 - 372 WP_017417608.1 XkdW family protein -
QTN49_RS13325 (2724108) 2724108..2724470 - 363 WP_014721043.1 hypothetical protein -
QTN49_RS13330 (2724581) 2724581..2725132 - 552 Protein_2627 terminase -
QTN49_RS13335 (2725245) 2725245..2725757 - 513 WP_017417605.1 sigma-70 family RNA polymerase sigma factor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SpoIISA, type II toxin-antitoxin system

(3-239)

Antitoxin

Antitoxin SpoIISB

(1-56)


Sequences

Toxin        


Download         Length: 249 a.a.        Molecular weight: 29107.60 Da        Isoelectric Point: 4.7755

>T284663 WP_263611996.1 NZ_CP128504:2720047-2720793 [Bacillus velezensis]
MLLFFQIMVWTMAAALILYVYASWRYEAKVKEKMFAIRKTWYLLFVLGSMVYWTYDPESLFAAWRQYLIVAVCFALIDAF
IFLSAYIKKLAGNELETDTREILEENNEMLHSYLEKLKTYQYLLKNEPIHVYYGSTEAYAEGISRLLAAYAEKMNVTASL
CDYSAQSDKDRLTEHMPDTADVQSRLNRKDVYYDQKGRLVLIPFTVQNRHYVIKLTSENLLTEFDYLLFTSLTSIYDLML
PIEEEGDG

Download         Length: 747 bp

Antitoxin


Download         Length: 57 a.a.        Molecular weight: 6676.74 Da        Isoelectric Point: 10.9273

>AT284663 WP_003154807.1 NZ_CP128504:2720794-2720964 [Bacillus velezensis]
MEQAFQNGQPEQRAKPFKMFKKRSMTSIASYQVSPHTARIFKENERLIDKYKQKKA

Download         Length: 171 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB I2HQ14

References