284661

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) spoIISABC/SpoIISA-SpoIISB
Location 2903111..2904028 Replicon chromosome
Accession NZ_CP128503
Organism Bacillus velezensis strain SRCM123422

Toxin (Protein)


Gene name spoIISA Uniprot ID I2HQ15
Locus tag QTN48_RS14725 Protein ID WP_007407256.1
Coordinates 2903111..2903857 (+) Length 249 a.a.

Antitoxin (Protein)


Gene name spoIISB Uniprot ID I2HQ14
Locus tag QTN48_RS14730 Protein ID WP_003154807.1
Coordinates 2903858..2904028 (+) Length 57 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QTN48_RS14705 (2898514) 2898514..2899449 - 936 WP_237586758.1 ring-cleaving dioxygenase -
QTN48_RS14710 (2899776) 2899776..2901092 + 1317 WP_007610842.1 amino acid permease -
QTN48_RS14715 (2901379) 2901379..2901996 + 618 WP_003154804.1 DUF47 domain-containing protein -
QTN48_RS14720 (2902009) 2902009..2903007 + 999 WP_017417610.1 inorganic phosphate transporter -
QTN48_RS14725 (2903111) 2903111..2903857 + 747 WP_007407256.1 type II toxin-antitoxin system SpoIISA family toxin Toxin
QTN48_RS14730 (2903858) 2903858..2904028 + 171 WP_003154807.1 type II toxin-antitoxin system SpoIISB family antitoxin Antitoxin
QTN48_RS14735 (2904125) 2904125..2904250 + 126 WP_003154809.1 hypothetical protein -
QTN48_RS14740 (2904285) 2904285..2905163 - 879 WP_007407257.1 N-acetylmuramoyl-L-alanine amidase -
QTN48_RS14745 (2905177) 2905177..2905440 - 264 WP_003154813.1 phage holin -
QTN48_RS14750 (2905454) 2905454..2905717 - 264 WP_021493821.1 hemolysin XhlA family protein -
QTN48_RS14755 (2905769) 2905769..2906530 - 762 WP_025649639.1 hypothetical protein -
QTN48_RS14760 (2906587) 2906587..2906784 - 198 WP_007610833.1 XkdX family protein -
QTN48_RS14765 (2906789) 2906789..2907160 - 372 WP_017417608.1 XkdW family protein -
QTN48_RS14770 (2907173) 2907173..2907535 - 363 WP_014721043.1 hypothetical protein -
QTN48_RS14775 (2907646) 2907646..2908197 - 552 Protein_2915 terminase -
QTN48_RS14780 (2908310) 2908310..2908822 - 513 WP_017417605.1 sigma-70 family RNA polymerase sigma factor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SpoIISA, type II toxin-antitoxin system

(3-239)

Antitoxin

Antitoxin SpoIISB

(1-56)


Sequences

Toxin        


Download         Length: 249 a.a.        Molecular weight: 29077.57 Da        Isoelectric Point: 4.7755

>T284661 WP_007407256.1 NZ_CP128503:2903111-2903857 [Bacillus velezensis]
MLLFFQIMVWTMAAALILYVYASWRYEAKVKEKMFAIRKTWYLLFVLGSMVYWTYDPESLFAAWRQYLIVAVCFALIDAF
IFLSAYIKKLAGNELETDTREILEENNEMLHSYLEKLKTYQYLLKNEPIHVYYGSTEAYAEGISRLLAAYAEKMNVTASL
CDYSAQSDKDRLTEHMPDAADVQSRLNRKDVYYDQKGRLVLIPFTVQNRHYVIKLTSENLLTEFDYLLFTSLTSIYDLML
PIEEEGDG

Download         Length: 747 bp

Antitoxin


Download         Length: 57 a.a.        Molecular weight: 6676.74 Da        Isoelectric Point: 10.9273

>AT284661 WP_003154807.1 NZ_CP128503:2903858-2904028 [Bacillus velezensis]
MEQAFQNGQPEQRAKPFKMFKKRSMTSIASYQVSPHTARIFKENERLIDKYKQKKA

Download         Length: 171 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB I2HQ15

Antitoxin

Source ID Structure
AlphaFold DB I2HQ14

References