284656

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) spoIISABC/SpoIISA-SpoIISB
Location 1198603..1199519 Replicon chromosome
Accession NZ_CP128501
Organism Bacillus amyloliquefaciens strain SRCM123386

Toxin (Protein)


Gene name spoIISA Uniprot ID A0A7U5AVM4
Locus tag QTN46_RS06480 Protein ID WP_013351967.1
Coordinates 1198773..1199519 (-) Length 249 a.a.

Antitoxin (Protein)


Gene name spoIISB Uniprot ID I2HQ14
Locus tag QTN46_RS06475 Protein ID WP_003154807.1
Coordinates 1198603..1198773 (-) Length 57 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QTN46_RS06435 (1193744) 1193744..1195507 + 1764 WP_014470496.1 hypothetical protein -
QTN46_RS06440 (1195519) 1195519..1195845 + 327 WP_014470495.1 XkdW family protein -
QTN46_RS06445 (1195845) 1195845..1196009 + 165 WP_014470494.1 XkdX family protein -
QTN46_RS06450 (1196061) 1196061..1196861 + 801 WP_289394458.1 phage portal protein -
QTN46_RS06455 (1196915) 1196915..1197178 + 264 WP_013351964.1 hemolysin XhlA family protein -
QTN46_RS06460 (1197192) 1197192..1197455 + 264 WP_014470492.1 phage holin -
QTN46_RS06465 (1197469) 1197469..1198347 + 879 WP_014470491.1 N-acetylmuramoyl-L-alanine amidase -
QTN46_RS06470 (1198381) 1198381..1198506 - 126 WP_003154809.1 hypothetical protein -
QTN46_RS06475 (1198603) 1198603..1198773 - 171 WP_003154807.1 type II toxin-antitoxin system SpoIISB family antitoxin Antitoxin
QTN46_RS06480 (1198773) 1198773..1199519 - 747 WP_013351967.1 type II toxin-antitoxin system SpoIISA family toxin Toxin
QTN46_RS06485 (1199627) 1199627..1200625 - 999 WP_013351968.1 inorganic phosphate transporter -
QTN46_RS06490 (1200638) 1200638..1201255 - 618 WP_003154804.1 DUF47 domain-containing protein -
QTN46_RS06495 (1201540) 1201540..1202856 - 1317 WP_013351969.1 amino acid permease -
QTN46_RS06500 (1203180) 1203180..1204130 + 951 WP_013351970.1 ring-cleaving dioxygenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SpoIISA, type II toxin-antitoxin system

(3-239)

Antitoxin

Antitoxin SpoIISB

(1-56)


Sequences

Toxin        


Download         Length: 249 a.a.        Molecular weight: 29054.53 Da        Isoelectric Point: 4.6839

>T284656 WP_013351967.1 NZ_CP128501:c1199519-1198773 [Bacillus amyloliquefaciens]
MLLFYQIMVWTMAAALILYVYASWRYEAKVKEKMFAIRKTWYLLFVVGAMVYWTYDPESLFAAWRQYLIVAVCFALIDAF
IFLSAYIKKLAGNELETDTREILEENNEMLHSYLEKLKTYQYLLKNEPIHVYYGSTEAYAEGISRLLAAYAEKMNVTASL
CDYSAQSDKDRLTEHMPDAADVQSRLNRKDVYYDQKGRLVLIPFTVQNRQYVIKLTSENLLTEFDYLLFTSLTSIYDLML
PIEEEGDG

Download         Length: 747 bp

Antitoxin


Download         Length: 57 a.a.        Molecular weight: 6676.74 Da        Isoelectric Point: 10.9273

>AT284656 WP_003154807.1 NZ_CP128501:c1198773-1198603 [Bacillus amyloliquefaciens]
MEQAFQNGQPEQRAKPFKMFKKRSMTSIASYQVSPHTARIFKENERLIDKYKQKKA

Download         Length: 171 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7U5AVM4

Antitoxin

Source ID Structure
AlphaFold DB I2HQ14

References