284653

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) spoIISABC/SpoIISA-SpoIISB
Location 2574784..2575700 Replicon chromosome
Accession NZ_CP128500
Organism Bacillus amyloliquefaciens strain SRCM123364

Toxin (Protein)


Gene name spoIISA Uniprot ID A0A7U5AVM4
Locus tag QTN45_RS13065 Protein ID WP_013351967.1
Coordinates 2574784..2575530 (+) Length 249 a.a.

Antitoxin (Protein)


Gene name spoIISB Uniprot ID I2HQ14
Locus tag QTN45_RS13070 Protein ID WP_003154807.1
Coordinates 2575530..2575700 (+) Length 57 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QTN45_RS13045 (QTN45_13045) 2570173..2571123 - 951 WP_013351970.1 ring-cleaving dioxygenase -
QTN45_RS13050 (QTN45_13050) 2571447..2572763 + 1317 WP_013351969.1 amino acid permease -
QTN45_RS13055 (QTN45_13055) 2573048..2573665 + 618 WP_003154804.1 DUF47 domain-containing protein -
QTN45_RS13060 (QTN45_13060) 2573678..2574676 + 999 WP_013351968.1 inorganic phosphate transporter -
QTN45_RS13065 (QTN45_13065) 2574784..2575530 + 747 WP_013351967.1 type II toxin-antitoxin system SpoIISA family toxin Toxin
QTN45_RS13070 (QTN45_13070) 2575530..2575700 + 171 WP_003154807.1 type II toxin-antitoxin system SpoIISB family antitoxin Antitoxin
QTN45_RS13075 (QTN45_13075) 2575797..2575922 + 126 WP_003154809.1 hypothetical protein -
QTN45_RS13080 (QTN45_13080) 2575956..2576834 - 879 WP_014470491.1 N-acetylmuramoyl-L-alanine amidase -
QTN45_RS13085 (QTN45_13085) 2576848..2577111 - 264 WP_014470492.1 phage holin -
QTN45_RS13090 (QTN45_13090) 2577125..2577388 - 264 WP_013351964.1 hemolysin XhlA family protein -
QTN45_RS13095 (QTN45_13095) 2577442..2578239 - 798 WP_014470493.1 hypothetical protein -
QTN45_RS13100 (QTN45_13100) 2578294..2578458 - 165 WP_014470494.1 XkdX family protein -
QTN45_RS13105 (QTN45_13105) 2578458..2578784 - 327 WP_014470495.1 XkdW family protein -
QTN45_RS13110 (QTN45_13110) 2578796..2580559 - 1764 WP_014470496.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SpoIISA, type II toxin-antitoxin system

(3-239)

Antitoxin

Antitoxin SpoIISB

(1-56)


Sequences

Toxin        


Download         Length: 249 a.a.        Molecular weight: 29054.53 Da        Isoelectric Point: 4.6839

>T284653 WP_013351967.1 NZ_CP128500:2574784-2575530 [Bacillus amyloliquefaciens]
MLLFYQIMVWTMAAALILYVYASWRYEAKVKEKMFAIRKTWYLLFVVGAMVYWTYDPESLFAAWRQYLIVAVCFALIDAF
IFLSAYIKKLAGNELETDTREILEENNEMLHSYLEKLKTYQYLLKNEPIHVYYGSTEAYAEGISRLLAAYAEKMNVTASL
CDYSAQSDKDRLTEHMPDAADVQSRLNRKDVYYDQKGRLVLIPFTVQNRQYVIKLTSENLLTEFDYLLFTSLTSIYDLML
PIEEEGDG

Download         Length: 747 bp

Antitoxin


Download         Length: 57 a.a.        Molecular weight: 6676.74 Da        Isoelectric Point: 10.9273

>AT284653 WP_003154807.1 NZ_CP128500:2575530-2575700 [Bacillus amyloliquefaciens]
MEQAFQNGQPEQRAKPFKMFKKRSMTSIASYQVSPHTARIFKENERLIDKYKQKKA

Download         Length: 171 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7U5AVM4

Antitoxin

Source ID Structure
AlphaFold DB I2HQ14

References