284647

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 127326..127830 Replicon plasmid pHR1a
Accession NZ_CP128493
Organism Novosphingobium resinovorum strain HR1a

Toxin (Protein)


Gene name pasB Uniprot ID -
Locus tag QUC32_RS27405 Protein ID WP_211152060.1
Coordinates 127326..127619 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID T0IKR4
Locus tag QUC32_RS27410 Protein ID WP_021235306.1
Coordinates 127603..127830 (-) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QUC32_RS27395 (QUC32_27395) 125073..125966 + 894 WP_211152059.1 SDR family oxidoreductase -
QUC32_RS27400 (QUC32_27400) 126813..127274 - 462 WP_008828892.1 hypothetical protein -
QUC32_RS27405 (QUC32_27405) 127326..127619 - 294 WP_211152060.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QUC32_RS27410 (QUC32_27410) 127603..127830 - 228 WP_021235306.1 DUF6290 family protein Antitoxin
QUC32_RS27415 (QUC32_27415) 127886..128395 - 510 WP_211152061.1 hypothetical protein -
QUC32_RS27420 (QUC32_27420) 128412..128561 - 150 WP_248006420.1 hypothetical protein -
QUC32_RS27425 (QUC32_27425) 128623..129366 - 744 WP_289357715.1 hypothetical protein -
QUC32_RS27430 (QUC32_27430) 129596..129871 + 276 WP_008830594.1 hypothetical protein -
QUC32_RS27435 (QUC32_27435) 131022..131405 + 384 WP_008830595.1 transposase -
QUC32_RS27440 (QUC32_27440) 131712..131999 - 288 WP_008830597.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - htpB / katA 1..819262 819262


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(22-86)

Antitoxin

Protein of unknown function DUF6290

(1-71)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10874.57 Da        Isoelectric Point: 10.0135

>T284647 WP_211152060.1 NZ_CP128493:c127619-127326 [Novosphingobium resinovorum]
MAWRIELSSSAEKSLSKLDCQTAKRIITFPRERVAAGEDPRASGKPLSGPLAGRWRYRVGDYRIVCEIEDGRLVVLVLTV
GHRSGIYRCPPKDIHNP

Download         Length: 294 bp

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8466.50 Da        Isoelectric Point: 4.4066

>AT284647 WP_021235306.1 NZ_CP128493:c127830-127603 [Novosphingobium resinovorum]
MATSVRLAPEVEQRLDHLASATGRTKAYYLREIIERGLEDMEDIYLSDKVLEDIRAGRETASSLDDVEKRLGLAD

Download         Length: 228 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB T0IKR4

References