Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemIK/PRK09907-MazE
Location 60874..61478 Replicon plasmid pLI0213a
Accession NZ_CP128469
Organism Macrococcus bovicus strain LI0213

Toxin (Protein)


Gene name pemK Uniprot ID -
Locus tag QSV55_RS00400 Protein ID WP_289649408.1
Coordinates 61131..61478 (+) Length 116 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag QSV55_RS00395 Protein ID WP_289649407.1
Coordinates 60874..61137 (+) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QSV55_RS00380 (QSV55_00380) 56057..59857 + 3801 WP_289649404.1 hypothetical protein -
QSV55_RS00385 (QSV55_00385) 59908..60231 + 324 WP_289649405.1 DUF5592 family protein -
QSV55_RS00390 (QSV55_00390) 60231..60818 + 588 WP_289649406.1 hypothetical protein -
QSV55_RS00395 (QSV55_00395) 60874..61137 + 264 WP_289649407.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
QSV55_RS00400 (QSV55_00400) 61131..61478 + 348 WP_289649408.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
QSV55_RS00405 (QSV55_00405) 61632..63614 + 1983 WP_289649409.1 hypothetical protein -
QSV55_RS00410 (QSV55_00410) 63631..64086 + 456 WP_289649410.1 hypothetical protein -
QSV55_RS00415 (QSV55_00415) 64162..65301 + 1140 WP_289649411.1 CHAP domain-containing protein -
QSV55_RS00420 (QSV55_00420) 65314..65916 + 603 WP_289649412.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..66682 66682


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(7-109)

Antitoxin

SpoVT-AbrB domain

(13-55)


Sequences

Toxin        


Download         Length: 116 a.a.        Molecular weight: 13140.01 Da        Isoelectric Point: 5.6262

>T284625 WP_289649408.1 NZ_CP128469:61131-61478 [Macrococcus bovicus]
MVSKVSQGDIFYVNFNPSRGHEQKNHRPALAISHDMVRDNSDMTIVVPISQTDRDFPMYYPLTTTQLVKGKVLLDQSIAL
DLTARNVTADEVVETLSKEELEKIINRYKLLFTID

Download         Length: 348 bp

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9881.23 Da        Isoelectric Point: 5.7012

>AT284625 WP_289649407.1 NZ_CP128469:60874-61137 [Macrococcus bovicus]
MTTLEAKTKITGWGNSKGLRIPRKFLETLHISDNQEMQISVKNNSLVITPVTEEPNSIHELFAGWKDDGIRGNELDWGMA
KGEELKW

Download         Length: 264 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References