Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1930030..1930174 Replicon chromosome
Accession NZ_CP128466
Organism Klebsiella variicola strain 22KM2707

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1930066..1930168 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1930030..1930174 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QSV42_RS09700 (QSV42_09700) 1925160..1927220 + 2061 WP_046881615.1 oligopeptidase B -
QSV42_RS09705 (QSV42_09705) 1927224..1927883 - 660 WP_008804267.1 exodeoxyribonuclease X -
QSV42_RS09710 (QSV42_09710) 1927962..1928192 - 231 WP_012541260.1 DNA polymerase III subunit theta -
QSV42_RS09715 (QSV42_09715) 1928306..1928680 + 375 WP_038421459.1 CopC domain-containing protein YobA -
QSV42_RS09720 (QSV42_09720) 1928684..1929553 + 870 WP_012541262.1 copper homeostasis membrane protein CopD -
QSV42_RS09725 (QSV42_09725) 1929570..1929908 + 339 WP_008804271.1 YebY family protein -
- 1930030..1930174 - 145 - - Antitoxin
- 1930066..1930168 + 103 - - Toxin
QSV42_RS09730 (QSV42_09730) 1930553..1930696 - 144 WP_046878768.1 Ecr family regulatory small membrane protein -
QSV42_RS09735 (QSV42_09735) 1930800..1931768 - 969 WP_162493241.1 VirK/YbjX family protein -
QSV42_RS09740 (QSV42_09740) 1931925..1932578 + 654 WP_008804273.1 protein-serine/threonine phosphatase -
QSV42_RS09745 (QSV42_09745) 1932575..1932766 - 192 WP_002911395.1 YebW family protein -
QSV42_RS09750 (QSV42_09750) 1932864..1933103 - 240 WP_002911393.1 YebV family protein -
QSV42_RS09755 (QSV42_09755) 1933219..1934652 - 1434 WP_289642575.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T284614 NZ_CP128466:1930066-1930168 [Klebsiella variicola]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 145 bp

>AT284614 NZ_CP128466:c1930174-1930030 [Klebsiella variicola]
ACCGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References