Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 3752528..3753345 Replicon chromosome
Accession NZ_CP128435
Organism Morganella morganii subsp. morganii strain QLYYMMQL588

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag QSV29_RS18115 Protein ID WP_024473607.1
Coordinates 3752528..3753034 (-) Length 169 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag QSV29_RS18120 Protein ID WP_024473608.1
Coordinates 3753037..3753345 (-) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QSV29_RS18080 3747892..3748515 - 624 WP_024473603.1 thiol:disulfide interchange protein DsbA -
QSV29_RS18085 3748534..3749529 - 996 WP_024473604.1 serine/threonine protein kinase -
QSV29_RS18090 3749529..3749798 - 270 WP_004240741.1 YihD family protein -
QSV29_RS18095 3750019..3750591 + 573 Protein_3512 molybdenum cofactor guanylyltransferase MobA -
QSV29_RS18100 3750598..3751116 + 519 WP_236595626.1 molybdopterin-guanine dinucleotide biosynthesis protein MobB -
QSV29_RS18105 3751326..3751628 + 303 WP_004240743.1 HdeA/HdeB family chaperone -
QSV29_RS18110 3751756..3752277 + 522 WP_024473606.1 isopentenyl-diphosphate Delta-isomerase -
QSV29_RS18115 3752528..3753034 - 507 WP_024473607.1 GNAT family N-acetyltransferase Toxin
QSV29_RS18120 3753037..3753345 - 309 WP_024473608.1 DUF1778 domain-containing protein Antitoxin
QSV29_RS18125 3753478..3754830 - 1353 WP_024473609.1 glutathione-disulfide reductase -
QSV29_RS18130 3754900..3755742 - 843 WP_024473610.1 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ -
QSV29_RS18135 3755932..3756321 + 390 WP_004236536.1 DUF1090 domain-containing protein -
QSV29_RS18140 3756712..3757704 + 993 WP_024473611.1 inner membrane protein YhjD -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(44-143)

Antitoxin

Vibrio phage ICP1, Orf50

(21-94)


Sequences

Toxin        


Download         Length: 169 a.a.        Molecular weight: 18635.56 Da        Isoelectric Point: 9.8376

>T284568 WP_024473607.1 NZ_CP128435:c3753034-3752528 [Morganella morganii subsp. morganii]
MNLTAPEPLQQHHDFTVFQSGEESLNHWLKTRALQNQQSGASRTFVVCHHNRIMAYYALSTGVITCSQAAGRFRRNMPPE
IPVILLGRLAVDESVKGRGIGRGLIKDAALRVLQAAGIVGIRGIVVRALSDNARRFYEYTGFMPSPADPMLLMITLRDLQ
LVTGIYSE

Download         Length: 507 bp

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 11542.22 Da        Isoelectric Point: 9.8096

>AT284568 WP_024473608.1 NZ_CP128435:c3753345-3753037 [Morganella morganii subsp. morganii]
MTKHTDEQHPVSGVNITRSTLNLRIKPEDKILIDRAAHAAGKNRTEFVLEAARRAAEETLANLRVIDVSTDVYQQFITRL
DMAPQSGEALRKTMLTKALWEK

Download         Length: 309 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References