Detailed information of TA system TA284563

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): ykfI-yfjZ/CbtA-CbeA
• Location: 419923..420626
• Replicon: chromosome
• Accession: NZ_CP128435
• Organism: Morganella morganii subsp. morganii strain QLYYMMQL588

Toxin (Protein)

• Gene name: ykfI
• Uniprot ID: -
• Locus tag: QSV29_RS02030
• Protein ID: WP_289648771.1
• Coordinates: 420285..420626 (+)
• Length: 114 a.a.

Antitoxin (Protein)

• Gene name: yfjZ
• Uniprot ID: -
• Locus tag: QSV29_RS02025
• Protein ID: WP_024474307.1
• Coordinates: 419923..420249 (+)
• Length: 109 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
QSV29_RS01995	415386..416261	+	876	WP_024474301.1	dynamin family protein	-
QSV29_RS02000	416474..417175	+	702	WP_024474302.1	WYL domain-containing protein	-
QSV29_RS02005	417181..417813	+	633	WP_024474303.1	hypothetical protein	-
QSV29_RS02010	417982..418392	+	411	WP_154902787.1	IrmA family protein	-
QSV29_RS02015	418512..419333	+	822	WP_024474305.1	DUF932 domain-containing protein	-
QSV29_RS02020	419405..419878	+	474	WP_024474306.1	DNA repair protein RadC	-
QSV29_RS02025	419923..420249	+	327	WP_024474307.1	type IV toxin-antitoxin system YeeU family antitoxin	Antitoxin
QSV29_RS02030	420285..420626	+	342	WP_289648771.1	TA system toxin CbtA family protein	Toxin
QSV29_RS02035	420741..421574	+	834	WP_024474309.1	DUF4942 domain-containing protein	-
QSV29_RS02040	421651..421899	+	249	WP_000535213.1	ribbon-helix-helix domain-containing protein	-
QSV29_RS02045	421903..422178	+	276	WP_024474310.1	type II toxin-antitoxin system RelE/ParE family toxin	-
QSV29_RS02050	422295..423092	+	798	WP_024474311.1	helix-turn-helix domain-containing protein	-
QSV29_RS02055	423615..424778	+	1164	Protein_379	IS3 family transposase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	393872..431107	37235

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• CbtA toxin of type IV toxin-antitoxin system (1-108)

Antitoxin

• Antitoxin CbeA (8-107)

Sequences

Toxin

Protein

• Length: 114 a.a.
• Molecular weight: 12817.73 Da
• Isoelectric Point: 10.4209

>T284563 WP_289648771.1 NZ_CP128435:420285-420626 [Morganella morganii subsp. morganii]
MKTLPASTLRAAKPCPTPVVVWQTLLTRLLGQHYGLTLNDTPFSDENVIQEHINAGITLADAVNFLVEKYELVRIDRRGF
SRQEQSPYLRAVDILRARQATGLLRRSHHPSTR

Nucleotide

• Length: 342 bp

Antitoxin

Protein

• Length: 109 a.a.
• Molecular weight: 12449.12 Da
• Isoelectric Point: 6.0722

>AT284563 WP_024474307.1 NZ_CP128435:419923-420249 [Morganella morganii subsp. morganii]
MEKNDPIEWGLRRDITPRVGARLVQERNQLHYLADRAGVTGIFNEAESRKLNAAFPHFVEQMELMLLSGELNPRYAHCVT
LYHDGFTCEADTLGSYGYVYIVIYPTQR

Nucleotide

• Length: 327 bp