Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 3569101..3569705 Replicon chromosome
Accession NZ_CP128416
Organism Rhizobium sp. CSC1952

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag QTA58_RS17380 Protein ID WP_289669780.1
Coordinates 3569388..3569705 (-) Length 106 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag QTA58_RS17375 Protein ID WP_289669778.1
Coordinates 3569101..3569403 (-) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QTA58_RS17340 (QTA58_17340) 3564506..3565129 + 624 WP_289669774.1 DUF1285 domain-containing protein -
QTA58_RS17345 (QTA58_17345) 3565126..3565761 + 636 WP_085424946.1 CoA pyrophosphatase -
QTA58_RS17350 (QTA58_17350) 3565758..3567020 + 1263 WP_289669775.1 CCA tRNA nucleotidyltransferase -
QTA58_RS17355 (QTA58_17355) 3567036..3567230 - 195 WP_085424944.1 DUF1059 domain-containing protein -
QTA58_RS17360 (QTA58_17360) 3567330..3567599 - 270 WP_085424943.1 hypothetical protein -
QTA58_RS17365 (QTA58_17365) 3567735..3568646 - 912 WP_289669776.1 oxygen-dependent coproporphyrinogen oxidase -
QTA58_RS17370 (QTA58_17370) 3568847..3569104 + 258 WP_085424941.1 hypothetical protein -
QTA58_RS17375 (QTA58_17375) 3569101..3569403 - 303 WP_289669778.1 putative addiction module antidote protein Antitoxin
QTA58_RS17380 (QTA58_17380) 3569388..3569705 - 318 WP_289669780.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QTA58_RS17385 (QTA58_17385) 3569767..3570246 - 480 WP_289669782.1 redox-sensitive transcriptional activator SoxR -
QTA58_RS17390 (QTA58_17390) 3570338..3570913 + 576 WP_289669784.1 NAD(P)H-dependent oxidoreductase -
QTA58_RS17395 (QTA58_17395) 3570913..3572139 + 1227 WP_289669786.1 MFS transporter -
QTA58_RS17400 (QTA58_17400) 3572151..3573803 - 1653 WP_289669788.1 Na/Pi cotransporter family protein -
QTA58_RS17405 (QTA58_17405) 3573943..3574404 - 462 WP_289673199.1 tRNA (cytidine(34)-2'-O)-methyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-94)

Antitoxin

Cro/C1-type helix-turn-helix domain

(47-90)


Sequences

Toxin        


Download         Length: 106 a.a.        Molecular weight: 11949.66 Da        Isoelectric Point: 9.8431

>T284559 WP_289669780.1 NZ_CP128416:c3569705-3569388 [Rhizobium sp. CSC1952]
MFEIYSTKIFRTWVDGLRDRRAVTRIFARIARAEEGNLGDVKPVGEGVSEMRIHYGPGYRVYFTRRGKVVLLLLCGGDKD
SQASDIAEAKRVAQNSGEISEWPWK

Download         Length: 318 bp

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 10870.55 Da        Isoelectric Point: 4.5098

>AT284559 WP_289669778.1 NZ_CP128416:c3569403-3569101 [Rhizobium sp. CSC1952]
MALEIRRFDIAEHLNSDEDIQEFMVAAFEDGDPAFIAKCLGIVARAQNMSKLARDVGMSRAALYKALSGEGNPEFATILK
VMKALGLELTPVLARTEDAA

Download         Length: 303 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References