284558

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/HicA-HicB
Location 3465866..3466464 Replicon chromosome
Accession NZ_CP128416
Organism Rhizobium sp. CSC1952

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag QTA58_RS16880 Protein ID WP_289669703.1
Coordinates 3466276..3466464 (-) Length 63 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag QTA58_RS16875 Protein ID WP_289669702.1
Coordinates 3465866..3466273 (-) Length 136 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QTA58_RS16830 (QTA58_16830) 3461327..3461824 + 498 WP_085425040.1 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase -
QTA58_RS16835 (QTA58_16835) 3461825..3462847 + 1023 WP_085425039.1 allantoicase -
QTA58_RS16840 (QTA58_16840) 3462905..3463195 + 291 WP_085425038.1 nucleotidyltransferase family protein -
QTA58_RS16845 (QTA58_16845) 3463192..3463536 + 345 WP_085425037.1 DUF86 domain-containing protein -
QTA58_RS16850 (QTA58_16850) 3463603..3463893 + 291 WP_085425036.1 nucleotidyltransferase family protein -
QTA58_RS16855 (QTA58_16855) 3463890..3464252 + 363 WP_289669698.1 DUF86 domain-containing protein -
QTA58_RS16860 (QTA58_16860) 3464267..3464767 + 501 WP_289669699.1 ureidoglycolate lyase -
QTA58_RS16865 (QTA58_16865) 3464764..3465120 + 357 WP_289669700.1 hydroxyisourate hydrolase -
QTA58_RS16870 (QTA58_16870) 3465120..3465869 + 750 WP_289669701.1 metallophosphoesterase family protein -
QTA58_RS16875 (QTA58_16875) 3465866..3466273 - 408 WP_289669702.1 type II toxin-antitoxin system HicB family antitoxin Antitoxin
QTA58_RS16880 (QTA58_16880) 3466276..3466464 - 189 WP_289669703.1 type II toxin-antitoxin system HicA family toxin Toxin
QTA58_RS16885 (QTA58_16885) 3466578..3467330 + 753 WP_289669704.1 hypothetical protein -
QTA58_RS16890 (QTA58_16890) 3467361..3468506 - 1146 WP_289669705.1 alpha-hydroxy acid oxidase -
QTA58_RS16895 (QTA58_16895) 3468600..3469922 - 1323 WP_289673195.1 guanine deaminase -
QTA58_RS16900 (QTA58_16900) 3469949..3471175 - 1227 WP_289669706.1 urate hydroxylase PuuD -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HicA mRNA interferase family

(4-59)

Antitoxin

HicB-like antitoxin of toxin-antitoxin system

(4-124)


Sequences

Toxin        


Download         Length: 63 a.a.        Molecular weight: 6959.19 Da        Isoelectric Point: 11.4650

>T284558 WP_289669703.1 NZ_CP128416:c3466464-3466276 [Rhizobium sp. CSC1952]
MKSAEVIALLRKDGWTEVGQKGSHVQFKHPHKPGRVTVPHPKRDIPLGTLRSIEKQAGLKLR

Download         Length: 189 bp

Antitoxin


Download         Length: 136 a.a.        Molecular weight: 14703.44 Da        Isoelectric Point: 4.3878

>AT284558 WP_289669702.1 NZ_CP128416:c3466273-3465866 [Rhizobium sp. CSC1952]
MSNYIGLIHKEADSDYGVSFPDFPGAVTAGSTLDEARRMAEEALAFHVEGMIEDGETIPEPSSLESVMADPDNRDAVAIL
VSLKTQAAKAVRINITLPEDILQRIDRFAEANGLSRSGFLARAARREIERNTTPN

Download         Length: 408 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References