Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PRK09907-MazE
Location 3131210..3131787 Replicon chromosome
Accession NZ_CP128416
Organism Rhizobium sp. CSC1952

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag QTA58_RS15195 Protein ID WP_289669494.1
Coordinates 3131449..3131787 (+) Length 113 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag QTA58_RS15190 Protein ID WP_289669493.1
Coordinates 3131210..3131452 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QTA58_RS15165 (QTA58_15165) 3126406..3126768 - 363 WP_037077221.1 response regulator CpdR1 -
QTA58_RS15170 (QTA58_15170) 3127217..3128104 + 888 WP_289669491.1 N-formylglutamate amidohydrolase -
QTA58_RS15175 (QTA58_15175) 3128426..3129202 + 777 WP_085420198.1 histidinol-phosphatase -
QTA58_RS15180 (QTA58_15180) 3129210..3130178 - 969 WP_289669492.1 alpha/beta hydrolase -
QTA58_RS15185 (QTA58_15185) 3130572..3131054 + 483 WP_085420772.1 Hsp20 family protein -
QTA58_RS15190 (QTA58_15190) 3131210..3131452 + 243 WP_289669493.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
QTA58_RS15195 (QTA58_15195) 3131449..3131787 + 339 WP_289669494.1 endoribonuclease MazF Toxin
QTA58_RS15200 (QTA58_15200) 3131801..3132799 - 999 WP_289669495.1 bile acid:sodium symporter family protein -
QTA58_RS15205 (QTA58_15205) 3132888..3133733 + 846 WP_289669496.1 LysR family transcriptional regulator -
QTA58_RS15210 (QTA58_15210) 3133811..3134863 - 1053 WP_289669497.1 low specificity L-threonine aldolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(10-106)

Antitoxin

SpoVT-AbrB domain

(6-48)


Sequences

Toxin        


Download         Length: 113 a.a.        Molecular weight: 12277.12 Da        Isoelectric Point: 10.2276

>T284557 WP_289669494.1 NZ_CP128416:3131449-3131787 [Rhizobium sp. CSC1952]
MTSASYVPDAGDIVWLQFSPQAGHGQVGHRPAVVLTPASYNRFRLMLCCPMTTKRKGYPFEVAIAGDRESVVLADQVKSL
DWRARNAQRKGRVSDHELGEVRAKAAALIGKP

Download         Length: 339 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8714.91 Da        Isoelectric Point: 4.2696

>AT284557 WP_289669493.1 NZ_CP128416:3131210-3131452 [Rhizobium sp. CSC1952]
MRVTVKKWGNSASVRIPAAVMEAARLEVDAVVDVSEENGRIVIEPIRDAEFDLDKLIAGITPENLHEEVDFGGPVGKETL

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References