Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) TsaAT/-
Location 699886..700362 Replicon chromosome
Accession NZ_CP128387
Organism Staphylococcus aureus strain 22-042

Toxin (Protein)


Gene name TsaT Uniprot ID T1Y7S2
Locus tag QTN90_RS03300 Protein ID WP_000052076.1
Coordinates 700174..700362 (+) Length 63 a.a.

Antitoxin (Protein)


Gene name TsaA Uniprot ID T1Y6P8
Locus tag QTN90_RS03295 Protein ID WP_001059690.1
Coordinates 699886..700146 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QTN90_RS03260 (QTN90_03260) 695284..696000 - 717 WP_000150026.1 type I 3-dehydroquinate dehydratase -
QTN90_RS03265 (QTN90_03265) 696148..696570 + 423 WP_000974452.1 organic hydroperoxide resistance protein -
QTN90_RS03270 (QTN90_03270) 696969..697463 + 495 WP_000569881.1 GNAT family N-acetyltransferase -
QTN90_RS03275 (QTN90_03275) 697612..698229 + 618 WP_000255562.1 LysE/ArgO family amino acid transporter -
QTN90_RS03280 (QTN90_03280) 698302..698883 - 582 WP_001140696.1 histidine phosphatase family protein -
QTN90_RS03285 (QTN90_03285) 699108..699344 + 237 WP_000368687.1 hypothetical protein -
QTN90_RS03290 (QTN90_03290) 699341..699544 - 204 WP_000145163.1 sterile alpha motif-like domain-containing protein -
QTN90_RS03295 (QTN90_03295) 699886..700146 + 261 WP_001059690.1 hypothetical protein Antitoxin
QTN90_RS03300 (QTN90_03300) 700174..700362 + 189 WP_000052076.1 hypothetical protein Toxin
QTN90_RS03305 (QTN90_03305) 700550..701119 + 570 WP_001106655.1 lipoprotein N-acylation protein LnsA -
QTN90_RS03310 (QTN90_03310) 701207..701491 + 285 WP_001004403.1 hypothetical protein -
QTN90_RS03315 (QTN90_03315) 701552..701770 + 219 WP_000005881.1 hypothetical protein -
QTN90_RS03320 (QTN90_03320) 702267..702467 - 201 WP_001059082.1 cold-shock protein -
QTN90_RS03325 (QTN90_03325) 702824..703510 - 687 WP_001574556.1 thermonuclease family protein -
QTN90_RS03330 (QTN90_03330) 703851..704333 - 483 WP_000824489.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 63 a.a.        Molecular weight: 7142.82 Da        Isoelectric Point: 9.9971

>T284514 WP_000052076.1 NZ_CP128387:700174-700362 [Staphylococcus aureus]
MSLHFAILFWLALIFLVAATFILVLMKKTGKESKKESYLSFTVILYIFGFAILIYTFIFGVL

Download         Length: 189 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9940.09 Da        Isoelectric Point: 4.0624

>AT284514 WP_001059690.1 NZ_CP128387:699886-700146 [Staphylococcus aureus]
MNNILLNAINIVITTTFVIFNILITYNKDLDDLCWLLPGIIICGVILIVSFTIAMITKNWLSEILFFINIVLVLYYIYPI
FYSFIG

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0E0VP18

Antitoxin

Source ID Structure
AlphaFold DB A0A0E0VN56

References