Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-YefM
Location 5388290..5388795 Replicon chromosome
Accession NZ_CP128260
Organism Pseudomonas fluorescens strain PH.SM

Toxin (Protein)


Gene name relE Uniprot ID Q3K782
Locus tag QR290_RS24130 Protein ID WP_011335833.1
Coordinates 5388541..5388795 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag QR290_RS24125 Protein ID WP_115079126.1
Coordinates 5388290..5388544 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QR290_RS24100 (QR290_24100) 5383607..5383972 + 366 WP_289203759.1 hypothetical protein -
QR290_RS24105 (QR290_24105) 5383997..5384746 - 750 WP_289203760.1 hypothetical protein -
QR290_RS24110 (QR290_24110) 5384867..5385241 + 375 WP_115079123.1 hypothetical protein -
QR290_RS24115 (QR290_24115) 5385353..5386099 + 747 WP_289203761.1 hypothetical protein -
QR290_RS24120 (QR290_24120) 5386171..5388090 + 1920 WP_289203762.1 alkaline phosphatase D family protein -
QR290_RS24125 (QR290_24125) 5388290..5388544 + 255 WP_115079126.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
QR290_RS24130 (QR290_24130) 5388541..5388795 + 255 WP_011335833.1 Txe/YoeB family addiction module toxin Toxin
QR290_RS24135 (QR290_24135) 5388789..5389976 - 1188 WP_115079127.1 aspartate aminotransferase family protein -
QR290_RS24140 (QR290_24140) 5390079..5390984 + 906 WP_289203763.1 LysR family transcriptional regulator -
QR290_RS24145 (QR290_24145) 5391030..5391434 + 405 WP_289203764.1 GNAT family N-acetyltransferase -
QR290_RS24150 (QR290_24150) 5391501..5392016 + 516 WP_115079130.1 hypothetical protein -
QR290_RS24155 (QR290_24155) 5392035..5392739 - 705 WP_115079131.1 peptide-methionine (S)-S-oxide reductase MsrA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9950.59 Da        Isoelectric Point: 9.6300

>T284490 WP_011335833.1 NZ_CP128260:5388541-5388795 [Pseudomonas fluorescens]
MKIQFTPTGWEDYLWFQQNDKAGLKRINLLIKAIQRQPFEGLGKPEPLKHNMSGFWSRRITAEHRLVYAIVDGEICVITC
RFHY

Download         Length: 255 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9437.82 Da        Isoelectric Point: 4.8090

>AT284490 WP_115079126.1 NZ_CP128260:5388290-5388544 [Pseudomonas fluorescens]
MDTINYTTARAHLAETMDRVNEDCAPLLVTRQKGEPVVMMSLAEYNALEETAYLLRSPANAERLIKSIGEMRAGKAQVRQ
LIEE

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB Q3K782

Antitoxin

Source ID Structure

References