Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 432183..432699 Replicon chromosome
Accession NZ_CP128260
Organism Pseudomonas fluorescens strain PH.SM

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QR290_RS01890 Protein ID WP_289204204.1
Coordinates 432418..432699 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0C1VYZ2
Locus tag QR290_RS01885 Protein ID WP_039773014.1
Coordinates 432183..432428 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QR290_RS01850 (QR290_01850) 427455..428060 + 606 WP_115076104.1 adenylyl-sulfate kinase -
QR290_RS01855 (QR290_01855) 428057..428842 + 786 WP_289204201.1 aspartyl/asparaginyl beta-hydroxylase domain-containing protein -
QR290_RS01860 (QR290_01860) 428830..429804 + 975 WP_289204202.1 sulfotransferase family protein -
QR290_RS01865 (QR290_01865) 429770..430528 - 759 WP_007957673.1 slipin family protein -
QR290_RS01870 (QR290_01870) 430531..431058 - 528 WP_289204203.1 NfeD family protein -
QR290_RS01875 (QR290_01875) 431255..431716 + 462 WP_207984640.1 YbaK/EbsC family protein -
QR290_RS01880 (QR290_01880) 431845..432087 + 243 WP_039773016.1 DUF2789 domain-containing protein -
QR290_RS01885 (QR290_01885) 432183..432428 + 246 WP_039773014.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
QR290_RS01890 (QR290_01890) 432418..432699 + 282 WP_289204204.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QR290_RS01895 (QR290_01895) 432824..433252 + 429 WP_011331882.1 winged helix DNA-binding protein -
QR290_RS01900 (QR290_01900) 433249..435312 + 2064 WP_289204205.1 FUSC family protein -
QR290_RS01905 (QR290_01905) 435309..435518 + 210 WP_007957657.1 DUF1656 domain-containing protein -
QR290_RS01910 (QR290_01910) 435515..436402 + 888 WP_007957655.1 HlyD family secretion protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(9-67)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10957.77 Da        Isoelectric Point: 10.4588

>T284482 WP_289204204.1 NZ_CP128260:432418-432699 [Pseudomonas fluorescens]
MTYKLEFLPSAHKEWNKLGHTLRDQFKKKLAERLERPRIPADSLHGMPDCYKIKLKASGYRLVYQVIEERVVVSVVAVGK
RERGDVYENSKRR

Download         Length: 282 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8776.06 Da        Isoelectric Point: 4.4988

>AT284482 WP_039773014.1 NZ_CP128260:432183-432428 [Pseudomonas fluorescens]
MQSVLADMAVSVSELKKNPSAVLNGAHGGAVAVLNHNRVMGYMVPADVYEAMMERLDDLELAEIVRSRSHETPIPVSLDD
L

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A0C1VYZ2

References