Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-Phd
Location 2747651..2748309 Replicon chromosome
Accession NZ_CP128233
Organism Paralcaligenes sp. CC-YST667

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag N7E01_RS15160 Protein ID WP_289173476.1
Coordinates 2747651..2748064 (-) Length 138 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag N7E01_RS15165 Protein ID WP_289173477.1
Coordinates 2748061..2748309 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N7E01_RS15135 (N7E01_15135) 2743049..2743525 - 477 WP_289173471.1 TIGR03759 family integrating conjugative element protein -
N7E01_RS15140 (N7E01_15140) 2743671..2744765 + 1095 WP_289173472.1 hypothetical protein -
N7E01_RS15145 (N7E01_15145) 2745226..2745480 + 255 WP_289173473.1 hypothetical protein -
N7E01_RS15150 (N7E01_15150) 2745616..2746041 + 426 WP_289173474.1 hypothetical protein -
N7E01_RS15155 (N7E01_15155) 2746499..2747365 + 867 WP_289173475.1 hypothetical protein -
N7E01_RS15160 (N7E01_15160) 2747651..2748064 - 414 WP_289173476.1 type II toxin-antitoxin system VapC family toxin Toxin
N7E01_RS15165 (N7E01_15165) 2748061..2748309 - 249 WP_289173477.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
N7E01_RS15170 (N7E01_15170) 2748421..2748708 + 288 WP_289173478.1 hypothetical protein -
N7E01_RS15175 (N7E01_15175) 2748701..2749165 + 465 WP_289173479.1 hypothetical protein -
N7E01_RS15180 (N7E01_15180) 2749627..2750031 + 405 WP_289173480.1 group II truncated hemoglobin -
N7E01_RS15185 (N7E01_15185) 2750021..2750290 + 270 WP_289173481.1 hypothetical protein -
N7E01_RS15190 (N7E01_15190) 2750329..2751045 - 717 WP_289173482.1 SIMPL domain-containing protein -
N7E01_RS15195 (N7E01_15195) 2751082..2752230 - 1149 WP_289173483.1 M20 aminoacylase family protein -
N7E01_RS15200 (N7E01_15200) 2752365..2753309 - 945 WP_289173484.1 MFS transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 2672837..2769058 96221


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-121)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-62)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 15104.27 Da        Isoelectric Point: 4.8781

>T284456 WP_289173476.1 NZ_CP128233:c2748064-2747651 [Paralcaligenes sp. CC-YST667]
MSYLIDTNVLSELRRKAPDPGVVAWFSQRPASTLHLSVLTLGEIRKDVEGVSDEARRQTLLDWLETDLPTFFTGRVLPVD
AAVADRWGRLVATAGRPLPAIDSLLAATALEHDLVLVTRNAKDFAGLPIDIFNPWSN

Download         Length: 414 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9518.74 Da        Isoelectric Point: 7.0130

>AT284456 WP_289173477.1 NZ_CP128233:c2748309-2748061 [Paralcaligenes sp. CC-YST667]
MQTWQMQEAKARMSEVVKRAQDQPQDITLHGKSVAVVISRETFDRLSQSQGSLVDFMRRSPLYEANDIAFERDRSLTREV
AF

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References