Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 2544754..2545310 Replicon chromosome
Accession NZ_CP128233
Organism Paralcaligenes sp. CC-YST667

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag N7E01_RS14000 Protein ID WP_289175822.1
Coordinates 2545044..2545310 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag N7E01_RS13995 Protein ID WP_289173302.1
Coordinates 2544754..2545047 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N7E01_RS13980 (N7E01_13980) 2540950..2541822 + 873 WP_289173300.1 PAS domain S-box protein -
N7E01_RS13985 (N7E01_13985) 2541974..2543488 + 1515 WP_289175821.1 PAS domain-containing protein -
N7E01_RS13990 (N7E01_13990) 2543506..2544615 + 1110 WP_289173301.1 EAL domain-containing response regulator -
N7E01_RS13995 (N7E01_13995) 2544754..2545047 - 294 WP_289173302.1 putative addiction module antidote protein Antitoxin
N7E01_RS14000 (N7E01_14000) 2545044..2545310 - 267 WP_289175822.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
N7E01_RS14005 (N7E01_14005) 2545635..2546954 + 1320 WP_289173303.1 IS1380 family transposase -
N7E01_RS14015 (N7E01_14015) 2547518..2548294 - 777 WP_289173304.1 flagellar brake protein -
N7E01_RS14020 (N7E01_14020) 2548447..2549545 - 1099 Protein_2756 AI-2E family transporter -
N7E01_RS14025 (N7E01_14025) 2549728..2550309 + 582 WP_289173306.1 glycosyltransferase family 39 protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(9-77)

Antitoxin

Uncharacterized protein HI1420

(5-92)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10012.47 Da        Isoelectric Point: 10.3118

>T284454 WP_289175822.1 NZ_CP128233:c2545310-2545044 [Paralcaligenes sp. CC-YST667]
MAGLKDLRARAKIIIRSQQASQGNFGDVKPISDGVWEMRIHFGPGYRVYYAREGRTVYLLLTGGNKSSQKRDIETAVAMW
KQIQEEQP

Download         Length: 267 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10280.84 Da        Isoelectric Point: 4.8359

>AT284454 WP_289173302.1 NZ_CP128233:c2545047-2544754 [Paralcaligenes sp. CC-YST667]
MSTIKIAPFDAAEYLDSEEAIAEYLSAALEEDDPSLFLAALADVAKARGMTKMAKDAGVGRESLYKALAPGAKPRYDTVL
KLARAAGVKLTVEPIHA

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References