Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/COG5606-COG4679
Location 1377744..1378419 Replicon chromosome
Accession NZ_CP128233
Organism Paralcaligenes sp. CC-YST667

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag N7E01_RS07410 Protein ID WP_289175276.1
Coordinates 1378057..1378419 (-) Length 121 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag N7E01_RS07405 Protein ID WP_289175759.1
Coordinates 1377744..1378067 (-) Length 108 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N7E01_RS07385 (N7E01_07385) 1374361..1375521 - 1161 WP_289175272.1 hypothetical protein -
N7E01_RS07390 (N7E01_07390) 1375937..1376188 - 252 WP_289175758.1 helix-turn-helix transcriptional regulator -
N7E01_RS07395 (N7E01_07395) 1376238..1376614 - 377 Protein_1452 type II toxin-antitoxin system RelE/ParE family toxin -
N7E01_RS07400 (N7E01_07400) 1376814..1377563 - 750 WP_289175274.1 Rpn family recombination-promoting nuclease/putative transposase -
N7E01_RS07405 (N7E01_07405) 1377744..1378067 - 324 WP_289175759.1 helix-turn-helix transcriptional regulator Antitoxin
N7E01_RS07410 (N7E01_07410) 1378057..1378419 - 363 WP_289175276.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
N7E01_RS07415 (N7E01_07415) 1378552..1378821 - 270 WP_289175760.1 type II toxin-antitoxin system RelB/DinJ family antitoxin -
N7E01_RS07420 (N7E01_07420) 1378917..1379204 - 288 WP_289175277.1 helix-turn-helix domain-containing protein -
N7E01_RS07425 (N7E01_07425) 1379302..1380540 + 1239 WP_289175279.1 tyrosine-type recombinase/integrase -
N7E01_RS07430 (N7E01_07430) 1380569..1380733 - 165 WP_289175280.1 hypothetical protein -
N7E01_RS07435 (N7E01_07435) 1380720..1381388 - 669 WP_289175282.1 hypothetical protein -
N7E01_RS07440 (N7E01_07440) 1381532..1381813 + 282 WP_289175284.1 hypothetical protein -
N7E01_RS07445 (N7E01_07445) 1381850..1382506 + 657 WP_289175286.1 NUDIX hydrolase -
N7E01_RS07450 (N7E01_07450) 1382503..1383093 - 591 WP_289175288.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(16-109)

Antitoxin

Cro/C1-type helix-turn-helix domain

(31-87)


Sequences

Toxin        


Download         Length: 121 a.a.        Molecular weight: 13267.30 Da        Isoelectric Point: 9.6418

>T284450 WP_289175276.1 NZ_CP128233:c1378419-1378057 [Paralcaligenes sp. CC-YST667]
MSPTIKPLRWIASSKKDLMAMPNDVQDTFGYALHLAQNGHKHPDAKPLKGFGGAGVLEVVEDFKGDTYRAVYTVRYLDTV
YVLHCFQKKSTQGISTPKPDVELIKARLKAIEAGIGGHRD

Download         Length: 363 bp

Antitoxin


Download         Length: 108 a.a.        Molecular weight: 11975.88 Da        Isoelectric Point: 9.9971

>AT284450 WP_289175759.1 NZ_CP128233:c1378067-1377744 [Paralcaligenes sp. CC-YST667]
IVINIEESSGNVYADLQMPEAEAMYVKARLASKISDIIRYRHLTQQQAAEILGISQPKLSGLLRGQFRGISEAKMIECLN
RLGRDVEIVVRKARGRQPQGQTHVVFA

Download         Length: 324 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References