Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 1299459..1299978 Replicon chromosome
Accession NZ_CP128233
Organism Paralcaligenes sp. CC-YST667

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag N7E01_RS06985 Protein ID WP_289175146.1
Coordinates 1299706..1299978 (+) Length 91 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag N7E01_RS06980 Protein ID WP_289175142.1
Coordinates 1299459..1299716 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N7E01_RS06950 (N7E01_06950) 1294895..1295622 + 728 Protein_1363 cyclase family protein -
N7E01_RS06955 (N7E01_06955) 1295648..1296376 + 729 WP_289175132.1 SDR family oxidoreductase -
N7E01_RS06960 (N7E01_06960) 1296576..1296842 + 267 WP_289175134.1 helix-turn-helix domain-containing protein -
N7E01_RS06965 (N7E01_06965) 1296839..1298145 + 1307 Protein_1366 HipA domain-containing protein -
N7E01_RS06970 (N7E01_06970) 1298184..1298870 + 687 WP_289175137.1 MFS transporter -
N7E01_RS06975 (N7E01_06975) 1298908..1299357 + 450 WP_289175139.1 MFS transporter -
N7E01_RS06980 (N7E01_06980) 1299459..1299716 + 258 WP_289175142.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
N7E01_RS06985 (N7E01_06985) 1299706..1299978 + 273 WP_289175146.1 Txe/YoeB family addiction module toxin Toxin
N7E01_RS06990 (N7E01_06990) 1299892..1303695 - 3804 Protein_1371 hydantoinase B/oxoprolinase family protein -
N7E01_RS06995 (N7E01_06995) 1303895..1304170 + 276 WP_289175147.1 type II toxin-antitoxin system prevent-host-death family antitoxin -
N7E01_RS07000 (N7E01_07000) 1304170..1304562 + 393 WP_289175756.1 type II toxin-antitoxin system RelE/ParE family toxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(11-90)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10808.48 Da        Isoelectric Point: 8.2656

>T284448 WP_289175146.1 NZ_CP128233:1299706-1299978 [Paralcaligenes sp. CC-YST667]
MPTRPEPKLLWTIAAWQDYEYWQGQDKKTLKRINTLIKDCMRHPFEGLGKPEPLKENLSGFWSRRIDDTHRLVYCVDEQG
LVIIACRYHY

Download         Length: 273 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9344.47 Da        Isoelectric Point: 4.2803

>AT284448 WP_289175142.1 NZ_CP128233:1299459-1299716 [Paralcaligenes sp. CC-YST667]
MRVVNFSEARNSLKLVIDQVINDADYTVIARRDAPDAVVMSLDTFNSLMETVHLLNSPANAAHLAQSIAQYREGNVITQA
LDDAD

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References