Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 1049064..1049686 Replicon chromosome
Accession NZ_CP128233
Organism Paralcaligenes sp. CC-YST667

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag N7E01_RS05580 Protein ID WP_289174880.1
Coordinates 1049064..1049372 (+) Length 103 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag N7E01_RS05585 Protein ID WP_289174881.1
Coordinates 1049375..1049686 (+) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N7E01_RS05555 (N7E01_05555) 1045022..1046002 - 981 WP_289174875.1 diguanylate cyclase -
N7E01_RS05560 (N7E01_05560) 1046033..1046959 - 927 WP_289174876.1 WYL domain-containing protein -
N7E01_RS05565 (N7E01_05565) 1047282..1047551 + 270 WP_289174877.1 CopG family transcriptional regulator -
N7E01_RS05570 (N7E01_05570) 1047538..1047906 + 369 WP_289174878.1 type II toxin-antitoxin system RelE/ParE family toxin -
N7E01_RS05575 (N7E01_05575) 1048172..1048864 - 693 WP_289174879.1 nitroreductase -
N7E01_RS05580 (N7E01_05580) 1049064..1049372 + 309 WP_289174880.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
N7E01_RS05585 (N7E01_05585) 1049375..1049686 + 312 WP_289174881.1 putative addiction module antidote protein Antitoxin
N7E01_RS05590 (N7E01_05590) 1050042..1050796 - 755 Protein_1091 NYN domain-containing protein -
N7E01_RS05595 (N7E01_05595) 1050904..1051218 - 315 WP_289174882.1 NIPSNAP family protein -
N7E01_RS05600 (N7E01_05600) 1051290..1051826 - 537 WP_289174883.1 DUF2058 domain-containing protein -
N7E01_RS05605 (N7E01_05605) 1051842..1052186 - 345 WP_289174884.1 zinc ribbon domain-containing protein YjdM -
N7E01_RS05610 (N7E01_05610) 1052548..1052898 + 351 WP_289174885.1 CocE/NonD family hydrolase -
N7E01_RS05615 (N7E01_05615) 1052826..1053452 + 627 WP_289175746.1 CocE/NonD family hydrolase -
N7E01_RS05620 (N7E01_05620) 1053403..1054491 + 1089 WP_289174886.1 CocE/NonD family hydrolase -
N7E01_RS05625 (N7E01_05625) 1054478..1054630 + 153 WP_289174887.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-96)

Antitoxin

Cro/C1-type helix-turn-helix domain

(51-95)


Sequences

Toxin        


Download         Length: 103 a.a.        Molecular weight: 11813.64 Da        Isoelectric Point: 9.7777

>T284447 WP_289174880.1 NZ_CP128233:1049064-1049372 [Paralcaligenes sp. CC-YST667]
MYTIKSLPEFDAWFDSLKDPTTRARLIRRLEKAERGLLGDVEPVGEGVNEMREFFGPGWRMYYIEQGDVLIVMLGGGSKV
TQTRDIKRAKKLARTLRYDEKT

Download         Length: 309 bp

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 11094.77 Da        Isoelectric Point: 8.9429

>AT284447 WP_289174881.1 NZ_CP128233:1049375-1049686 [Paralcaligenes sp. CC-YST667]
MDKKTIKVSDLPSFDPARYLRDDKDIAAYLTQIIEEGDSGELAHALGVAARARGMTQIAEAAGIGRESLYKALRADASPR
FDTIAKVCKALGVRIVVQAKHPA

Download         Length: 312 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References