Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapB(antitoxin)
Location 373291..373868 Replicon chromosome
Accession NZ_CP128233
Organism Paralcaligenes sp. CC-YST667

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag N7E01_RS01855 Protein ID WP_289174363.1
Coordinates 373291..373671 (-) Length 127 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag N7E01_RS01860 Protein ID WP_289174365.1
Coordinates 373668..373868 (-) Length 67 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N7E01_RS01825 (N7E01_01825) 368529..369800 + 1272 WP_289175707.1 hydantoinase B/oxoprolinase family protein -
N7E01_RS01830 (N7E01_01830) 369806..370267 + 462 WP_289174355.1 hypothetical protein -
N7E01_RS01835 (N7E01_01835) 370549..371154 + 606 WP_289174356.1 hypothetical protein -
N7E01_RS01840 (N7E01_01840) 371049..372233 + 1185 WP_289174358.1 GTP-binding protein -
N7E01_RS01845 (N7E01_01845) 372280..372717 + 438 WP_289174359.1 hypothetical protein -
N7E01_RS01850 (N7E01_01850) 372757..373242 + 486 WP_289174361.1 nucleoside 2-deoxyribosyltransferase -
N7E01_RS01855 (N7E01_01855) 373291..373671 - 381 WP_289174363.1 PIN domain-containing protein Toxin
N7E01_RS01860 (N7E01_01860) 373668..373868 - 201 WP_289174365.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
N7E01_RS01865 (N7E01_01865) 374170..374811 - 642 WP_289174367.1 lipocalin family protein -
N7E01_RS01870 (N7E01_01870) 374848..375639 - 792 WP_289174369.1 hypothetical protein -
N7E01_RS01875 (N7E01_01875) 375686..376483 - 798 WP_289174371.1 histidinol-phosphatase -
N7E01_RS01880 (N7E01_01880) 376662..377710 - 1049 Protein_368 NADP(H)-dependent aldo-keto reductase -
N7E01_RS01885 (N7E01_01885) 377880..378352 - 473 Protein_369 Dps family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-113)

Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-43)


Sequences

Toxin        


Download         Length: 127 a.a.        Molecular weight: 14333.88 Da        Isoelectric Point: 6.8614

>T284445 WP_289174363.1 NZ_CP128233:c373671-373291 [Paralcaligenes sp. CC-YST667]
MRRVLVDTSVWVEHFRNPNQALIELLLHDQVKIHPLIIGELACGTPPDRRNTLALLENLAQVRQASISEAMVFIERERLY
GQGCGLVDLLLLSSALMTEQTLIWTLDKRFGALAIRFNLMFMPVAH

Download         Length: 381 bp

Antitoxin


Download         Length: 67 a.a.        Molecular weight: 7268.36 Da        Isoelectric Point: 7.0118

>AT284445 WP_289174365.1 NZ_CP128233:c373868-373668 [Paralcaligenes sp. CC-YST667]
MRTTVTLDDALFKRALEVADPGMDKSELFREAVKTFIRVQSAKRLAALGGAAPDMADIPRRDPEHA

Download         Length: 201 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References