Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 1919841..1920406 Replicon chromosome
Accession NZ_CP128231
Organism Paraburkholderia bonniea strain BbQS395

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QS306_RS08365 Protein ID WP_153075451.1
Coordinates 1919841..1920212 (-) Length 124 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QS306_RS08370 Protein ID WP_153075452.1
Coordinates 1920209..1920406 (-) Length 66 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QS306_RS08355 (QS306_08355) 1917308..1917613 + 306 WP_286273106.1 hypothetical protein -
QS306_RS08360 (QS306_08360) 1918193..1918974 - 782 Protein_1624 IS5 family transposase -
QS306_RS08365 (QS306_08365) 1919841..1920212 - 372 WP_153075451.1 type II toxin-antitoxin system VapC family toxin Toxin
QS306_RS08370 (QS306_08370) 1920209..1920406 - 198 WP_153075452.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
QS306_RS08375 (QS306_08375) 1920539..1921625 + 1087 Protein_1627 IS3 family transposase -
QS306_RS08380 (QS306_08380) 1921828..1923570 - 1743 WP_286273107.1 30S ribosomal protein S12 methylthiotransferase accessory factor YcaO -
QS306_RS08385 (QS306_08385) 1924124..1925395 - 1272 WP_286273108.1 DUF1214 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1916960..1931808 14848
- flank IS/Tn - - 1921167..1921415 248


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-113)

Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-44)


Sequences

Toxin        


Download         Length: 124 a.a.        Molecular weight: 13604.82 Da        Isoelectric Point: 5.1298

>T284444 WP_153075451.1 NZ_CP128231:c1920212-1919841 [Paraburkholderia bonniea]
MILVDTSVWIDHINASDPMLITLLAEERVLAHPYVIGEISLGSLRSRDVVLGALLDLPRAPVATPDETFYLIEREGLFNR
GIGYVDTSLLASARLQPGITIWTRDKRLKKVADELNLGAMLAH

Download         Length: 372 bp

Antitoxin


Download         Length: 66 a.a.        Molecular weight: 7058.18 Da        Isoelectric Point: 11.0553

>AT284444 WP_153075452.1 NZ_CP128231:c1920406-1920209 [Paraburkholderia bonniea]
MRTTIALDDDLIAKAQAYTGVKEKTALVREALKALIQREAAKRLANLGGSQPGIKAAPRRRQNAE

Download         Length: 198 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References