Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | vapBC/- |
Location | 14749..15422 | Replicon | plasmid pPsv48A |
Accession | NC_019265 | ||
Organism | Pseudomonas savastanoi |
Toxin (Protein)
Gene name | vapC | Uniprot ID | H1ZWW2 |
Locus tag | PSA3335_RS00045 | Protein ID | WP_002556053.1 |
Coordinates | 14749..15168 (-) | Length | 140 a.a. |
Antitoxin (Protein)
Gene name | vapB | Uniprot ID | Q48B52 |
Locus tag | PSA3335_RS00050 | Protein ID | WP_003381346.1 |
Coordinates | 15165..15422 (-) | Length | 86 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
PSA3335_RS00040 (PSA3335_A0007) | 14076..14708 | - | 633 | WP_015060648.1 | recombinase family protein | - |
PSA3335_RS00045 (PSA3335_A0008) | 14749..15168 | - | 420 | WP_002556053.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
PSA3335_RS00050 (PSA3335_A0009) | 15165..15422 | - | 258 | WP_003381346.1 | Arc family DNA-binding protein | Antitoxin |
PSA3335_RS00055 | 15575..15856 | + | 282 | WP_060407302.1 | hypothetical protein | - |
PSA3335_RS00060 (PSA3335_A0011) | 15858..17054 | + | 1197 | WP_237772646.1 | IS91 family transposase | - |
PSA3335_RS00065 (PSA3335_A0013) | 17851..19073 | + | 1223 | WP_095178853.1 | IS3-like element IS51 family transposase | - |
PSA3335_RS00070 (PSA3335_A0014) | 19110..19796 | - | 687 | WP_244657733.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Non-Mobilizable plasmid | - | - | 1..80123 | 80123 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 140 a.a. Molecular weight: 15168.46 Da Isoelectric Point: 4.7010
>T28443 WP_002556053.1 NC_019265:c15168-14749 [Pseudomonas savastanoi pv. savastanoi]
MILLDTNVISEPQRREPNAHVLDWIDAQALETLYLSTITVAELRAGIALMPVGKRQDSLRENLEKHLLPMFANRVLSFDM
TCTKAYAELLAKSRAAGLAVETADAFIAAIALANGFTVATRDTGPFEAAGLNVINPWET
MILLDTNVISEPQRREPNAHVLDWIDAQALETLYLSTITVAELRAGIALMPVGKRQDSLRENLEKHLLPMFANRVLSFDM
TCTKAYAELLAKSRAAGLAVETADAFIAAIALANGFTVATRDTGPFEAAGLNVINPWET
Download Length: 420 bp
>T28443 NC_019265:c15168-14749 [Pseudomonas savastanoi pv. savastanoi]
ATGATCCTGCTCGATACGAACGTAATTTCAGAACCGCAGCGCCGAGAGCCCAATGCCCACGTCCTTGACTGGATCGACGC
ACAAGCGCTAGAAACGCTTTATCTGTCCACCATCACCGTAGCCGAGTTGCGTGCAGGTATCGCGCTGATGCCTGTCGGAA
AACGCCAGGATAGCTTGCGTGAAAACCTGGAAAAGCACCTGCTGCCGATGTTCGCCAATAGGGTGCTGTCGTTCGATATG
ACTTGTACGAAGGCTTATGCCGAGCTGCTGGCCAAGTCCCGCGCAGCCGGGTTGGCGGTCGAAACGGCAGATGCCTTCAT
TGCAGCCATCGCCCTCGCCAACGGCTTCACCGTCGCCACCCGTGACACTGGCCCTTTTGAGGCTGCCGGGTTGAACGTCA
TTAACCCCTGGGAAACGTAA
ATGATCCTGCTCGATACGAACGTAATTTCAGAACCGCAGCGCCGAGAGCCCAATGCCCACGTCCTTGACTGGATCGACGC
ACAAGCGCTAGAAACGCTTTATCTGTCCACCATCACCGTAGCCGAGTTGCGTGCAGGTATCGCGCTGATGCCTGTCGGAA
AACGCCAGGATAGCTTGCGTGAAAACCTGGAAAAGCACCTGCTGCCGATGTTCGCCAATAGGGTGCTGTCGTTCGATATG
ACTTGTACGAAGGCTTATGCCGAGCTGCTGGCCAAGTCCCGCGCAGCCGGGTTGGCGGTCGAAACGGCAGATGCCTTCAT
TGCAGCCATCGCCCTCGCCAACGGCTTCACCGTCGCCACCCGTGACACTGGCCCTTTTGAGGCTGCCGGGTTGAACGTCA
TTAACCCCTGGGAAACGTAA
Antitoxin
Download Length: 86 a.a. Molecular weight: 9401.62 Da Isoelectric Point: 9.0330
>AT28443 WP_003381346.1 NC_019265:c15422-15165 [Pseudomonas savastanoi pv. savastanoi]
VANVNVRNLPDEVHRAIRIQAALHGRSTEAEIRDILERAARPEGRVKLGSFLASIAREVGGLTDKEHTLFENTRITSPAR
AVSFE
VANVNVRNLPDEVHRAIRIQAALHGRSTEAEIRDILERAARPEGRVKLGSFLASIAREVGGLTDKEHTLFENTRITSPAR
AVSFE
Download Length: 258 bp
>AT28443 NC_019265:c15422-15165 [Pseudomonas savastanoi pv. savastanoi]
GTGGCAAACGTGAACGTAAGAAATCTACCCGATGAAGTGCATCGGGCCATCCGCATCCAAGCTGCCCTGCACGGGCGCAG
CACCGAGGCCGAAATACGCGACATCTTGGAGCGGGCGGCGAGACCCGAGGGACGTGTGAAACTTGGCTCGTTCCTGGCTT
CTATTGCCCGTGAGGTTGGTGGTCTGACCGATAAAGAACATACCTTGTTTGAGAACACGCGCATCACGTCTCCGGCCCGT
GCGGTGAGCTTTGAATGA
GTGGCAAACGTGAACGTAAGAAATCTACCCGATGAAGTGCATCGGGCCATCCGCATCCAAGCTGCCCTGCACGGGCGCAG
CACCGAGGCCGAAATACGCGACATCTTGGAGCGGGCGGCGAGACCCGAGGGACGTGTGAAACTTGGCTCGTTCCTGGCTT
CTATTGCCCGTGAGGTTGGTGGTCTGACCGATAAAGAACATACCTTGTTTGAGAACACGCGCATCACGTCTCCGGCCCGT
GCGGTGAGCTTTGAATGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A3M2ZA27 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | Q48B52 |