284410

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 1822946..1823426 Replicon chromosome
Accession NZ_CP128214
Organism Agrobacterium fabrum strain ARqua1

Toxin (Protein)


Gene name pasB Uniprot ID A9CK22
Locus tag QOV31_RS09015 Protein ID WP_010971059.1
Coordinates 1823157..1823426 (+) Length 90 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID A9CK21
Locus tag QOV31_RS09010 Protein ID WP_010971060.1
Coordinates 1822946..1823173 (+) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QOV31_RS08980 (QOV31_001784) 1817974..1818393 + 420 WP_230060738.1 hypothetical protein -
QOV31_RS08985 (QOV31_001785) 1818549..1818995 + 447 WP_006313161.1 DoxX family protein -
QOV31_RS08990 (QOV31_001786) 1819060..1819752 - 693 WP_010971064.1 ATP phosphoribosyltransferase -
QOV31_RS08995 (QOV31_001787) 1819749..1820876 - 1128 WP_010971063.1 ATP phosphoribosyltransferase regulatory subunit -
QOV31_RS09000 (QOV31_001788) 1820893..1821261 - 369 WP_010971062.1 VOC family protein -
QOV31_RS09005 (QOV31_001789) 1821266..1822789 - 1524 WP_010971061.1 histidine--tRNA ligase -
QOV31_RS09010 (QOV31_001790) 1822946..1823173 + 228 WP_010971060.1 DUF6290 family protein Antitoxin
QOV31_RS09015 (QOV31_001791) 1823157..1823426 + 270 WP_010971059.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QOV31_RS09020 (QOV31_001792) 1823433..1824197 + 765 WP_010971058.1 hypothetical protein -
QOV31_RS09025 (QOV31_001793) 1824223..1825140 - 918 WP_010971057.1 LysR family transcriptional regulator -
QOV31_RS09030 (QOV31_001794) 1825222..1826265 + 1044 WP_035256280.1 YeiH family protein -
QOV31_RS09035 (QOV31_001795) 1826291..1826734 - 444 WP_010972617.1 hypothetical protein -
QOV31_RS09040 (QOV31_001796) 1826731..1827360 - 630 WP_010971055.1 DNA-3-methyladenine glycosylase I -
QOV31_RS09045 (QOV31_001797) 1827599..1828375 + 777 WP_010971054.1 L,D-transpeptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-88)

Antitoxin

Protein of unknown function DUF6290

(6-73)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10746.46 Da        Isoelectric Point: 9.9414

>T284410 WP_010971059.1 NZ_CP128214:1823157-1823426 [Agrobacterium fabrum]
VIWTIEYHTLVQKEMRKINPEVRRRIRSFLHERLAALDDPRQIGATLQGSELGNFWRYRVGDYRIICDIQDQKLVVLVVE
IGHRREIYR

Download         Length: 270 bp

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8937.97 Da        Isoelectric Point: 4.7254

>AT284410 WP_010971060.1 NZ_CP128214:1822946-1823173 [Agrobacterium fabrum]
MSKQTAIRLPDETYERLKALSERTGRTSAYYIREAIEKHIEDMEDLYLAEEATRRIQRGESKIISAEEFWRDLDN

Download         Length: 228 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A9CK22

Antitoxin

Source ID Structure
AlphaFold DB A9CK21

References