Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 2221537..2222081 Replicon chromosome
Accession NZ_CP128204
Organism Vibrio furnissii strain VFBJ05

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QSU95_RS10325 Protein ID WP_172559614.1
Coordinates 2221537..2221836 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0Q2N1Z8
Locus tag QSU95_RS10330 Protein ID WP_055466056.1
Coordinates 2221824..2222081 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QSU95_RS10295 (QSU95_10295) 2216878..2217606 + 729 WP_004725097.1 FliA/WhiG family RNA polymerase sigma factor -
QSU95_RS10300 (QSU95_10300) 2217616..2218473 + 858 WP_004725096.1 flagellar motor stator protein MotA -
QSU95_RS10305 (QSU95_10305) 2218473..2219465 + 993 WP_154180241.1 flagellar motor protein MotB -
QSU95_RS10310 (QSU95_10310) 2219540..2219827 + 288 WP_232658001.1 hypothetical protein -
QSU95_RS10315 (QSU95_10315) 2219964..2220494 + 531 WP_055466057.1 copper resistance protein NlpE -
QSU95_RS10320 (QSU95_10320) 2220834..2221109 + 276 WP_004725092.1 hypothetical protein -
QSU95_RS10325 (QSU95_10325) 2221537..2221836 - 300 WP_172559614.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QSU95_RS10330 (QSU95_10330) 2221824..2222081 - 258 WP_055466056.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
QSU95_RS10335 (QSU95_10335) 2222229..2222705 - 477 WP_286210994.1 sensor protein -
QSU95_RS10340 (QSU95_10340) 2222772..2222861 - 90 WP_286212344.1 DUF3265 domain-containing protein -
QSU95_RS10345 (QSU95_10345) 2222889..2223812 - 924 WP_286210996.1 hypothetical protein -
QSU95_RS10350 (QSU95_10350) 2223910..2223999 - 90 Protein_1992 DUF3265 domain-containing protein -
QSU95_RS10355 (QSU95_10355) 2223971..2224930 - 960 WP_286210997.1 hypothetical protein -
QSU95_RS10360 (QSU95_10360) 2225399..2226163 - 765 WP_004725087.1 IclR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-71)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11475.40 Da        Isoelectric Point: 4.8604

>T284405 WP_172559614.1 NZ_CP128204:c2221836-2221537 [Vibrio furnissii]
MAEIIWTEPALSDLNDIAEYIALENVAAAKQLVQTIFAKVERLENFPESGRIPPELAHLSYRELVVNPCRIFYKFDGDKV
FILFVMRSERDLRKFLLGM

Download         Length: 300 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9659.20 Da        Isoelectric Point: 8.5255

>AT284405 WP_055466056.1 NZ_CP128204:c2222081-2221824 [Vibrio furnissii]
MKVELVTSLKRQATKILADLRSTKEPVLITEHGKPSAYLVDVEDYEFMQNRLAILEGIARGERAFADGKVVSHEEAKDKM
SKWLK

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A0Q2N1Z8

References