Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-YefM
Location 51098..51660 Replicon plasmid pVFBJ07-1
Accession NZ_CP128202
Organism Vibrio furnissii strain VFBJ07

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag QSU96_RS23520 Protein ID WP_038152854.1
Coordinates 51358..51660 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag QSU96_RS23515 Protein ID WP_004729600.1
Coordinates 51098..51343 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QSU96_RS23500 (QSU96_23500) 48683..48910 - 228 WP_038152853.1 hypothetical protein -
QSU96_RS23505 (QSU96_23505) 49140..50060 + 921 WP_286282545.1 IS5 family transposase -
QSU96_RS23510 (QSU96_23510) 50361..50897 - 537 Protein_44 recombinase family protein -
QSU96_RS23515 (QSU96_23515) 51098..51343 + 246 WP_004729600.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
QSU96_RS23520 (QSU96_23520) 51358..51660 + 303 WP_038152854.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QSU96_RS23525 (QSU96_23525) 51657..52259 - 603 WP_004729602.1 recombinase family protein -
QSU96_RS23530 (QSU96_23530) 52869..53945 - 1077 WP_038152856.1 replication initiation protein -
QSU96_RS23535 (QSU96_23535) 54889..55611 + 723 WP_004729604.1 hypothetical protein -
QSU96_RS23540 (QSU96_23540) 55601..56350 + 750 WP_119299138.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..71247 71247
- flank IS/Tn - - 49140..50060 920


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-89)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-56)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11644.32 Da        Isoelectric Point: 6.7572

>T284403 WP_038152854.1 NZ_CP128202:51358-51660 [Vibrio furnissii]
MSSYKLSPLAQSDLTDIRRYTIEHWGSTQWSVYFNELQESMSLLASNELIGIQIPEMGERYYRFPLKHHVIYYITQEDHI
VIVAVLGKHMSPAKHFASIS

Download         Length: 303 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9115.57 Da        Isoelectric Point: 4.5702

>AT284403 WP_004729600.1 NZ_CP128202:51098-51343 [Vibrio furnissii]
MQSLTANTAKTKFGDLLMKVQREPVQISKNGSPVAVMMSCEEYEQLEALKMMLVKSRFEQAEIDIRNGDLVDGDEFMKSL
A

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References