Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mosAT/AbiEii-AbiEi
Location 2705918..2707640 Replicon chromosome
Accession NZ_CP128200
Organism Vibrio furnissii strain VFBJ07

Toxin (Protein)


Gene name mosT Uniprot ID -
Locus tag QSU96_RS12650 Protein ID WP_169631892.1
Coordinates 2705918..2706856 (-) Length 313 a.a.

Antitoxin (Protein)


Gene name mosA Uniprot ID -
Locus tag QSU96_RS12655 Protein ID WP_169631891.1
Coordinates 2706849..2707640 (-) Length 264 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QSU96_RS12640 (QSU96_12640) 2701504..2702613 - 1110 WP_122067050.1 hypothetical protein -
QSU96_RS12645 (QSU96_12645) 2702610..2705339 - 2730 WP_122067049.1 DEAD/DEAH box helicase -
QSU96_RS12650 (QSU96_12650) 2705918..2706856 - 939 WP_169631892.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
QSU96_RS12655 (QSU96_12655) 2706849..2707640 - 792 WP_169631891.1 type IV toxin-antitoxin system AbiEi family antitoxin Antitoxin
QSU96_RS12660 (QSU96_12660) 2707860..2708246 - 387 WP_000180225.1 TraA family conjugative transfer protein -
QSU96_RS12665 (QSU96_12665) 2708243..2708815 - 573 WP_001944091.1 type IV conjugative transfer system lipoprotein TraV -
QSU96_RS12670 (QSU96_12670) 2708890..2710179 - 1290 WP_169631890.1 TraB/VirB10 family protein -
QSU96_RS12675 (QSU96_12675) 2710182..2711078 - 897 WP_180826067.1 type-F conjugative transfer system secretin TraK -
QSU96_RS12680 (QSU96_12680) 2711062..2711682 - 621 WP_008844781.1 TraE/TraK family type IV conjugative transfer system protein -
QSU96_RS12685 (QSU96_12685) 2711679..2711960 - 282 WP_000433891.1 type IV conjugative transfer system protein TraL -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element sul2 / aph(3'')-Ib / aph(6)-Id / floR / tet(A) / sul1 / aac(6')-IIa - 2663868..2756435 92567


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(14-278)

Antitoxin

Transcriptional regulator AbiEi antitoxin, N-terminal domain

(1-97)


Sequences

Toxin        


Download         Length: 313 a.a.        Molecular weight: 35436.75 Da        Isoelectric Point: 5.1051

>T284402 WP_169631892.1 NZ_CP128200:c2706856-2705918 [Vibrio furnissii]
MDKDSPYYKQVSLLIRMLPVVATETVFALKGGTAINLFVRDFPRLSVDIDLAYLPLEPRDEALVNVRAALQRITDRINTQ
PDIRAAFQDNKADELRIVVSSPVATIKIEVSPVARGTLHSAEIMPVQESVEDEFGYAEIQVVSLPDLYGGKLCAAMDRQH
PRDLFDVRMLLGSEGISREILVGFLTYTLSHPRPINEVMSPNWQPLNEKFQAEFDGMTFEKVECADLASVRPMMLMALQK
HFTERDHAFLMSFKRGQPDWALFDYPNAADLPAIRWKLQNINKLAKNQAKHQEQLDKLKQVLDDWLVNANAE

Download         Length: 939 bp

Antitoxin


Download         Length: 264 a.a.        Molecular weight: 30129.55 Da        Isoelectric Point: 9.5219

>AT284402 WP_169631891.1 NZ_CP128200:c2707640-2706849 [Vibrio furnissii]
MSSKINWLVAHTSPGALVLQQWLTENGVSYSLAQKYAQNGWLKKLCSGVYYRPDAQGDIKPTWVDAIQALNVQLGVSVHL
AGLSSLTHQGLSHYLQLNKERVWICVKNKSSLPKWFREFPYQNWFYCGNHKLEVNPEKDLKRITVKEKELTVSCAELAAY
EVVDGIGKLISFEHVAELFQGLVNLSPRKVQDILERSSSVQANRIFLFLGRYYDHQWVNRIDETRIKLGAGKRQVVEKGR
FDERYQITVPEILSVKKGEQHNG

Download         Length: 792 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References