Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 2214788..2215332 Replicon chromosome
Accession NZ_CP128200
Organism Vibrio furnissii strain VFBJ07

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QSU96_RS10235 Protein ID WP_286279486.1
Coordinates 2214788..2215087 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0Q2N1Z8
Locus tag QSU96_RS10240 Protein ID WP_055466056.1
Coordinates 2215075..2215332 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QSU96_RS10205 (QSU96_10205) 2210118..2210846 + 729 WP_172561535.1 FliA/WhiG family RNA polymerase sigma factor -
QSU96_RS10210 (QSU96_10210) 2210856..2211713 + 858 WP_004725096.1 flagellar motor stator protein MotA -
QSU96_RS10215 (QSU96_10215) 2211713..2212705 + 993 WP_055466059.1 flagellar motor protein MotB -
QSU96_RS10220 (QSU96_10220) 2212780..2213067 + 288 WP_014204723.1 hypothetical protein -
QSU96_RS10225 (QSU96_10225) 2213204..2213734 + 531 WP_004725093.1 copper resistance protein NlpE -
QSU96_RS10230 (QSU96_10230) 2214078..2214353 + 276 WP_004725092.1 hypothetical protein -
QSU96_RS10235 (QSU96_10235) 2214788..2215087 - 300 WP_286279486.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QSU96_RS10240 (QSU96_10240) 2215075..2215332 - 258 WP_055466056.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
QSU96_RS10245 (QSU96_10245) 2215547..2215987 - 441 WP_222731879.1 hypothetical protein -
QSU96_RS10250 (QSU96_10250) 2215984..2217090 - 1107 WP_286279492.1 hypothetical protein -
QSU96_RS10255 (QSU96_10255) 2217566..2218330 - 765 WP_286279493.1 IclR family transcriptional regulator -
QSU96_RS10260 (QSU96_10260) 2218445..2219752 - 1308 WP_024373226.1 TRAP transporter large permease -
QSU96_RS10265 (QSU96_10265) 2219762..2220289 - 528 WP_004725085.1 TRAP transporter small permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-85)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-71)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11451.41 Da        Isoelectric Point: 4.6561

>T284401 WP_286279486.1 NZ_CP128200:c2215087-2214788 [Vibrio furnissii]
MAEIIWTEPALSDLNDIAEYIALENVAAAKQLVQTIFAKVERLENFPESGRIPPELALLSYRELVVNPCRIFYKFDGDKV
FILFVMRSERDLRKFLLGM

Download         Length: 300 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9659.20 Da        Isoelectric Point: 8.5255

>AT284401 WP_055466056.1 NZ_CP128200:c2215332-2215075 [Vibrio furnissii]
MKVELVTSLKRQATKILADLRSTKEPVLITEHGKPSAYLVDVEDYEFMQNRLAILEGIARGERAFADGKVVSHEEAKDKM
SKWLK

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A0Q2N1Z8

References