Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 2370887..2371449 Replicon chromosome
Accession NZ_CP128197
Organism Gordonia sp. Swx-4

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PWF70_RS10735 Protein ID WP_286352949.1
Coordinates 2371159..2371449 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A6G7W6R5
Locus tag PWF70_RS10730 Protein ID WP_055477309.1
Coordinates 2370887..2371162 (+) Length 92 a.a.

Genomic Context

PWF70_RS10705PWF70_RS10715PWF70_RS10720PWF70_RS10730PWF70_RS10735PWF70_RS10750PWF70_RS10710PWF70_RS10725PWF70_RS10740PWF70_RS10745PWF70_RS10755PWF70_RS10760
Location: 2366737..2367384 (648 bp)
Type: Others
Protein ID: WP_035752370.1
Location: 2368058..2368891 (834 bp)
Type: Others
Protein ID: WP_035752376.1
Location: 2369219..2369596 (378 bp)
Type: Others
Protein ID: WP_035752553.1
Location: 2370887..2371162 (276 bp)
Type: Antitoxin
Protein ID: WP_055477309.1
Location: 2371159..2371449 (291 bp)
Type: Toxin
Protein ID: WP_286352949.1
Location: 2372692..2373045 (354 bp)
Type: Others
Protein ID: WP_055477306.1
Location: 2367418..2367807 (390 bp)
Type: Others
Protein ID: WP_035752373.1
Location: 2369726..2370409 (684 bp)
Type: Others
Protein ID: WP_051405879.1
Location: 2371468..2371674 (207 bp)
Type: Others
Protein ID: WP_055477311.1
Location: 2372342..2372575 (234 bp)
Type: Others
Protein ID: WP_055477307.1
Location: 2373164..2373403 (240 bp)
Type: Others
Protein ID: WP_055477305.1
Location: 2373438..2375498 (2061 bp)
Type: Others
Protein ID: WP_068970440.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
PWF70_RS10705 (PWF70_10705)2366737..2367384+648WP_035752370.1hypothetical protein-
PWF70_RS10710 (PWF70_10710)2367418..2367807-390WP_035752373.1DUF1304 domain-containing protein-
PWF70_RS10715 (PWF70_10715)2368058..2368891+834WP_035752376.1DUF4436 family protein-
PWF70_RS10720 (PWF70_10720)2369219..2369596+378WP_035752553.1SRPBCC family protein-
PWF70_RS10725 (PWF70_10725)2369726..2370409-684WP_051405879.1hypothetical protein-
PWF70_RS10730 (PWF70_10730)2370887..2371162+276WP_055477309.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
PWF70_RS10735 (PWF70_10735)2371159..2371449+291WP_286352949.1type II toxin-antitoxin system RelE/ParE family toxinToxin
PWF70_RS10740 (PWF70_10740)2371468..2371674-207WP_055477311.1hypothetical protein-
PWF70_RS10745 (PWF70_10745)2372342..2372575-234WP_055477307.1hypothetical protein-
PWF70_RS10750 (PWF70_10750)2372692..2373045+354WP_055477306.1hypothetical protein-
PWF70_RS10755 (PWF70_10755)2373164..2373403-240WP_055477305.1hypothetical protein-
PWF70_RS10760 (PWF70_10760)2373438..2375498-2061WP_068970440.1DEAD/DEAH box helicase family protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideGenomic island--2370887..241165940772


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(16-94)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10924.37 Da        Isoelectric Point: 9.7360

>T284400 WP_286352949.1 NZ_CP128197:2371159-2371449 [Gordonia sp. Swx-4]
MSDAPTDSSAPYRVDVASPARRDLQRLPSRIVHAVIEFISGPLAENPHRLSKPLRDDLADLHSARRGDYRILLRIDDPNH
TIVIVRIDHRAHAYRT

Download         Length: 291 bp

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 9718.86 Da        Isoelectric Point: 4.3809

>AT284400 WP_055477309.1 NZ_CP128197:2370887-2371162 [Gordonia sp. Swx-4]
MTTVPLGEAKDKLSALVDSAESTHDIITITKHGKPAAVLMSADDLESLHETIYWLSRAGVRDDVATADAEYAAGETVSID
DLRAEHGMPPK

Download         Length: 276 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A6G7W6R5

References