Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 2370887..2371449 Replicon chromosome
Accession NZ_CP128197
Organism Gordonia sp. Swx-4

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PWF70_RS10735 Protein ID WP_286352949.1
Coordinates 2371159..2371449 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A6G7W6R5
Locus tag PWF70_RS10730 Protein ID WP_055477309.1
Coordinates 2370887..2371162 (+) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PWF70_RS10705 (PWF70_10705) 2366737..2367384 + 648 WP_035752370.1 hypothetical protein -
PWF70_RS10710 (PWF70_10710) 2367418..2367807 - 390 WP_035752373.1 DUF1304 domain-containing protein -
PWF70_RS10715 (PWF70_10715) 2368058..2368891 + 834 WP_035752376.1 DUF4436 family protein -
PWF70_RS10720 (PWF70_10720) 2369219..2369596 + 378 WP_035752553.1 SRPBCC family protein -
PWF70_RS10725 (PWF70_10725) 2369726..2370409 - 684 WP_051405879.1 hypothetical protein -
PWF70_RS10730 (PWF70_10730) 2370887..2371162 + 276 WP_055477309.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
PWF70_RS10735 (PWF70_10735) 2371159..2371449 + 291 WP_286352949.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PWF70_RS10740 (PWF70_10740) 2371468..2371674 - 207 WP_055477311.1 hypothetical protein -
PWF70_RS10745 (PWF70_10745) 2372342..2372575 - 234 WP_055477307.1 hypothetical protein -
PWF70_RS10750 (PWF70_10750) 2372692..2373045 + 354 WP_055477306.1 hypothetical protein -
PWF70_RS10755 (PWF70_10755) 2373164..2373403 - 240 WP_055477305.1 hypothetical protein -
PWF70_RS10760 (PWF70_10760) 2373438..2375498 - 2061 WP_068970440.1 DEAD/DEAH box helicase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 2370887..2411659 40772


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(16-94)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10924.37 Da        Isoelectric Point: 9.7360

>T284400 WP_286352949.1 NZ_CP128197:2371159-2371449 [Gordonia sp. Swx-4]
MSDAPTDSSAPYRVDVASPARRDLQRLPSRIVHAVIEFISGPLAENPHRLSKPLRDDLADLHSARRGDYRILLRIDDPNH
TIVIVRIDHRAHAYRT

Download         Length: 291 bp

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 9718.86 Da        Isoelectric Point: 4.3809

>AT284400 WP_055477309.1 NZ_CP128197:2370887-2371162 [Gordonia sp. Swx-4]
MTTVPLGEAKDKLSALVDSAESTHDIITITKHGKPAAVLMSADDLESLHETIYWLSRAGVRDDVATADAEYAAGETVSID
DLRAEHGMPPK

Download         Length: 276 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A6G7W6R5

References